Centre of Expertise for Health and Work Ability, Finnish Institute of Occupational Health,Topeliuksenkatu 41 a A, Helsinki, Finland.
Am J Epidemiol. 2010 Jan 15;171(2):135-54. doi: 10.1093/aje/kwp356. Epub 2009 Dec 11.
This meta-analysis assessed the association between overweight/obesity and low back pain. The authors systematically searched the Medline (National Library of Medicine, Bethesda, Maryland) and Embase (Elsevier, Amsterdam, the Netherlands) databases until May 2009. Ninety-five studies were reviewed and 33 included in the meta-analyses. In cross-sectional studies, obesity was associated with increased prevalence of low back pain in the past 12 months (pooled odds ratio (OR) = 1.33, 95% confidence interval (CI): 1.14, 1.54), seeking care for low back pain (OR = 1.56, 95% CI: 1.46, 1.67), and chronic low back pain (OR = 1.43, 95% CI: 1.28, 1.60). Compared with non-overweight people, overweight people had a higher prevalence of low back pain but a lower prevalence of low back pain compared with obese people. In cohort studies, only obesity was associated with increased incidence of low back pain for > or =1 day in the past 12 months (OR = 1.53, 95% CI: 1.22, 1.92). Results remained consistent after adjusting for publication bias and limiting the analyses to studies that controlled for potential confounders. Findings indicate that overweight and obesity increase the risk of low back pain. Overweight and obesity have the strongest association with seeking care for low back pain and chronic low back pain.
这项荟萃分析评估了超重/肥胖与下腰痛之间的关系。作者系统地检索了 Medline（马里兰州贝塞斯达国立卫生研究院）和 Embase（荷兰阿姆斯特丹爱思唯尔公司）数据库，检索时间截至 2009 年 5 月。共评价了 95 项研究，其中 33 项纳入荟萃分析。在横断面研究中，肥胖与过去 12 个月内下腰痛的患病率增加相关（汇总比值比（OR）=1.33，95%可信区间（CI）：1.14，1.54），因下腰痛而寻求医疗帮助（OR=1.56，95%CI：1.46，1.67），以及慢性下腰痛（OR=1.43，95%CI：1.28，1.60）。与非超重人群相比，超重人群的下腰痛患病率较高，但与肥胖人群相比，其下腰痛患病率较低。在队列研究中，只有肥胖与过去 12 个月内下腰痛 1 天或以上的发病率增加相关（OR=1.53，95%CI：1.22，1.92）。在调整发表偏倚并将分析限于控制潜在混杂因素的研究后，结果仍然一致。研究结果表明超重和肥胖会增加下腰痛的风险。超重和肥胖与下腰痛的就诊和慢性下腰痛的相关性最强。
