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透析成本——基于区域人群的分析。

Costs of dialysis--a regional population-based analysis.

机构信息

German Diabetes Center, Institute of Biometrics and Epidemiology, Dusseldorf, Germany.

出版信息

Nephrol Dial Transplant. 2010 May;25(5):1647-52. doi: 10.1093/ndt/gfp672. Epub 2009 Dec 15.

Abstract

BACKGROUND

Population-based estimates of costs of renal replacement therapy are scarce in the literature. The aim of our study was to calculate the costs of long-term dialysis in 2006 on the basis of patient-specific data from a well-defined population in a region in western Germany (n = 310,757).

METHODS

Cost estimation was performed from the perspective of the statutory health insurance. All dialysis patients from the study region (n = 344, 54% male, mean age (+/-SD) 69 +/- 13 years, 42% diabetic) were assessed for the costs of the dialysis procedures, dialysis-related hospital admissions, outpatient contacts outside of our dialysis center, dialysis-related medication, patient transportation and related costs (e.g. reimbursement fees on the basis of the German diagnosis-related group system, price scales). We estimated the cumulative cost per patient year in 2006 (in Euros), along with the 10th and 90th percentiles and the 95% confidence intervals (CI) by using bootstrapping procedures.

RESULTS

The mean total dialysis-related cost in 2006 was 54,777 Euros (95% CI, 51,445-65,705) per patient year. The largest part of the costs (55%) was caused by the dialysis procedures, followed by the costs of medication (22%), hospitalization (14%) and transportation (8%). The total cost increased significantly with increasing age. No significant association was found between total cost and sex, dialysis strategy, end-stage renal disease duration and diabetes.

CONCLUSIONS

We present for the first time a cost estimation of dialysis in Germany on the basis of patient-level data in a population-based sample. Except age, patient characteristics were not significantly associated with costs. The largest part of the costs was caused by the dialysis procedures themselves; however, other dialysis-specific health care utilization also strongly contributed to the total cost.

摘要

背景

人群中对肾脏替代疗法费用的评估在文献中很少见。本研究的目的是基于德国西部一个地区明确界定的人群中患者个体数据计算 2006 年长期透析的费用(n = 310757)。

方法

费用评估从法定健康保险的角度进行。研究区域内的所有透析患者(n = 344,男性占 54%,平均年龄(+/-SD)为 69 +/- 13 岁,42%为糖尿病患者)均评估了透析程序、与透析相关的住院治疗、我院外透析中心的门诊接触、与透析相关的药物、患者交通和相关费用(如根据德国疾病诊断相关分组系统的报销费用、价格表)的费用。我们使用自举程序估计了每位患者 2006 年的累积费用(欧元),以及第 10、90 百分位数和 95%置信区间(CI)。

结果

2006 年每位患者的平均总透析相关费用为 54777 欧元(95%CI,51445-65705)。费用的最大部分(55%)由透析程序引起,其次是药物费用(22%)、住院费用(14%)和交通费用(8%)。总费用随年龄的增加而显著增加。总费用与性别、透析策略、终末期肾病持续时间和糖尿病无显著相关性。

结论

我们首次基于基于人群的样本中的患者个体数据对德国的透析费用进行了成本估算。除年龄外,患者特征与费用无显著相关性。费用的最大部分是由透析程序本身引起的;然而,其他与透析相关的医疗保健利用也对总费用有很大贡献。

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