Department of Biomedical Engineering, University of California, Davis, CA, USA.
Phys Med Biol. 2010 Jan 7;55(1):265-80. doi: 10.1088/0031-9155/55/1/016.
A positron emission tomography (PET) system or 'insert' has been constructed for placement and operation in the bore of a small animal magnetic resonance imaging (MRI) scanner to allow simultaneous MR and PET imaging. The insert contains electronics, components with a variety of magnetic properties and large continuous sheets of metal--all characteristics of an object that should, by conventional wisdom, never be placed in the bore of an MR scanner, especially near the imaging volume. There are a variety of ways the two systems might be expected to interact that could negatively impact the performance of either or both. In this article, the interaction mechanisms, particularly the impact of the PET insert and shielding on MR imaging, are defined and explored. Additionally, some of the difficulties in quantifying errors introduced into the MR images as a result of the presence of the PET components are demonstrated. Several different approaches are used to characterize image artifacts and determine optimal placement of the shielding. Data are also presented that suggest ways the shielding could be modified to reduce errors and enable placement closer to the isocenter of the magnet.
已构建正电子发射断层扫描 (PET) 系统或“插入件”,以放置和操作在小动物磁共振成像 (MRI) 扫描仪的孔中,以允许同时进行 MR 和 PET 成像。该插入件包含电子设备、具有各种磁性特性的组件和大型连续金属片——所有这些都是物体的特征,根据传统智慧,这些物体绝不应放置在 MRI 扫描仪的孔中,尤其是在成像区域附近。这两个系统可能会以多种方式相互作用,从而对任何一个系统的性能产生负面影响。在本文中,定义并探讨了相互作用机制,特别是 PET 插入件和屏蔽对 MR 成像的影响。此外,还演示了由于存在 PET 组件而导致 MR 图像中引入的误差进行量化的一些困难。使用几种不同的方法来描述图像伪影并确定屏蔽的最佳放置位置。还提供了一些数据,表明可以修改屏蔽的方式来减少错误并使屏蔽更接近磁铁的等中心。