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Ahmed 阀植入术治疗术前眼压小于 21mmHg 的结果。

Outcome of Ahmed valve implantation when preoperative IOP less than 21 mm Hg.

机构信息

Department of Ophthalmology and Visual Sciences, Toronto Western Hospital, Ontario, Canada.

出版信息

J Glaucoma. 2009 Dec;18(9):674-8. doi: 10.1097/IJG.0b013e31819c468e.

Abstract

PURPOSE

To examine the results of Ahmed glaucoma drainage device (GDD) implantation in patients with a preoperative intraocular pressure (IOP) of 20 mm Hg or less.

METHODS

Noncomparative retrospective case series.

RESULTS

Sixty-six surgeries in 63 patients were analyzed. Mean follow-up was 51 months. The mean drop in IOP was 3.8 mm Hg (23.3%, P<0.0001) at 12 months and 3.9 mm Hg (24.0%, P<0.0001) at final follow-up. The number of glaucoma medications used postoperatively was significantly less than preoperatively. Although the mean visual acuity was poorer postoperatively this did not reach statistical significance. Surgical success was defined as IOP > or =5 mm Hg and 20% lower than preoperatively with or without hypotensive therapy, visual acuity perception of light or better and no further glaucoma surgery. About 57.6% and 53.0% of patients were considered a success at 12 months and final follow-up, respectively. Fourteen patients (21.2%) underwent additional glaucoma surgery, 8 of which had a second Ahmed GDD inserted whereas 6 had cyclodestruction. All failures were due to inadequate IOP control or further glaucoma surgery, with no cases considered failures due to vision loss or hypotony. Perioperative complications developed in 6 cases (9.1%) whereas long-term problems related to surgery occurred in 8 cases (12.1%).

CONCLUSIONS

In patients with IOPs of 20 mm Hg or less who require IOPs in the low teens and below Ahmed GDD surgery does seem to be an effective option. The success rates of surgery, however, must be balanced against the risk of complications. In addition, the relative merits of Ahmed GDD implantation versus mitomycin trabeculectomy and/or nonvalved GDDs requires further investigation.

摘要

目的

研究术前眼压(IOP)在 20mmHg 或以下的患者行 Ahmed 青光眼引流装置(GDD)植入术后的效果。

方法

非对照回顾性病例系列研究。

结果

对 63 例 66 例手术进行了分析。平均随访时间为 51 个月。术后 12 个月时,IOP 平均下降 3.8mmHg(23.3%,P<0.0001),最终随访时,IOP 平均下降 3.9mmHg(24.0%,P<0.0001)。术后使用的青光眼药物数量明显少于术前。尽管术后平均视力较差,但差异无统计学意义。手术成功定义为 IOP>或=5mmHg,比术前降低 20%,且无需降压治疗,视力为光感或更好,无需进一步的青光眼手术。术后 12 个月和最终随访时,分别有 57.6%和 53.0%的患者被认为是成功的。14 例患者(21.2%)接受了额外的青光眼手术,其中 8 例再次植入 Ahmed GDD,6 例行睫状体破坏性手术。所有失败均由于眼压控制不佳或进一步的青光眼手术,无因视力丧失或低眼压而导致的失败病例。术中并发症发生 6 例(9.1%),术后长期并发症发生 8 例(12.1%)。

结论

对于需要将 IOP 控制在低十几的眼压在 20mmHg 或以下的患者,行 Ahmed GDD 手术似乎是一种有效的选择。然而,手术成功率必须与并发症的风险相平衡。此外,还需要进一步研究 Ahmed GDD 植入术与丝裂霉素小梁切除术和/或无阀 GDD 之间的相对优势。

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