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艾哈迈德青光眼引流阀植入术在埃及人群中的长期效果

Long-term results of Ahmed glaucoma valve implantation in Egyptian population.

作者信息

Elhefney Eman, Mokbel Tharwat, Abou Samra Waleed, Kishk Hanem, Mohsen Tarek, El-Kannishy Amr

机构信息

Department of Ophthalmology, Faculty of Medicine, Mansoura University, Mansoura 35516, Egypt.

出版信息

Int J Ophthalmol. 2018 Mar 18;11(3):416-421. doi: 10.18240/ijo.2018.03.11. eCollection 2018.

Abstract

AIM

To evaluate the long-term results and complications of Ahmed glaucoma valve (AGV) implantation in a cohort of Egyptian patients.

METHODS

A retrospective study of 124 eyes of 99 patients with refractory glaucoma who underwent AGV implantation and had a minimum follow-up of 5y was performed. All patients underwent complete ophthalmic examination and intraocular pressure (IOP) measurement before surgery and at 1d, weekly for the 1 month, 3, 6mo, and 1y after surgery and yearly afterward for 5y. IOP was measured by Goldmann applanation tonometry and/or Tono-Pen. Complications and the number of anti-glaucoma medications needed were recorded. Success was defined as IOP less than 21 mm Hg with or without anti-glaucoma medication and without additional glaucoma surgery.

RESULTS

Mean age was 23.1±19.9y. All eyes had at least one prior glaucoma surgery. IOP was reduced from a mean of 37.2±6.8 to 19.2±5.2 mm Hg after 5y follow-up with a reduced number of medications from 2.64±0.59 to 1.81±0.4. Complete and qualified success rates were 31.5% and 46.0% respectively at the end of follow-up. The most common complications were encapsulated cyst formation in 51 eyes (41.1%), complicated cataract in 9 eyes (7.25%), recessed tube in 8 eyes (6.45%), tube exposure in 6 eyes (4.8%) and corneal touch in 6 eyes (4.8%). Other complications included extruded AGV, endophthalmitis and persistent hypotony. Each of them was recorded in only 2 eyes (1.6%).

CONCLUSION

Although refractory glaucoma is a difficult problem to manage, AGV is effective and relatively safe procedure in treating refractory glaucoma in Egyptian patients with long-term follow-up. Encapsulated cyst formation was the most common complication, which limits successful IOP control after AGV implantation. However, effective complications management can improve the rate of success.

摘要

目的

评估在一组埃及患者中植入艾哈迈德青光眼引流阀(AGV)的长期效果及并发症。

方法

对99例难治性青光眼患者的124只眼进行回顾性研究,这些患者接受了AGV植入术,且至少随访5年。所有患者在手术前、术后1天、术后1个月每周、术后3个月、6个月、1年以及之后每年进行一次全面的眼科检查和眼压(IOP)测量,共5年。眼压通过Goldmann压平眼压计和/或Tono-Pen测量。记录并发症及所需抗青光眼药物的数量。成功定义为眼压低于21 mmHg,无论是否使用抗青光眼药物且无需额外的青光眼手术。

结果

平均年龄为23.1±19.9岁。所有患眼均至少接受过一次青光眼手术。经过5年随访,眼压从平均37.2±6.8 mmHg降至19.2±5.2 mmHg,药物数量从2.64±0.59减少至1.81±0.4。随访结束时,完全成功率和合格成功率分别为31.5%和46.0%。最常见的并发症为51只眼(41.1%)出现包裹性囊肿形成,9只眼(7.25%)出现复杂性白内障,8只眼(6.45%)出现引流管内陷,6只眼(4.8%)出现引流管暴露,6只眼(4.8%)出现角膜接触。其他并发症包括AGV脱出、眼内炎和持续性低眼压。每种并发症仅在2只眼(1.6%)中出现。

结论

尽管难治性青光眼是一个难以处理的问题,但在对埃及患者进行长期随访中,AGV植入术是治疗难治性青光眼的有效且相对安全的方法。包裹性囊肿形成是最常见的并发症,这限制了AGV植入术后眼压的有效控制。然而,有效的并发症管理可以提高成功率。

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