Salerno Christian, Bagnasco Gabriele, Comelli Mario, Panella Massimiliano
Dipartimento Prevenzione - SISP, ASL 11 Vercelli.
Ig Sanita Pubbl. 2009 Sep-Oct;65(5):467-74.
The main aim of this study was to assess the burden of cancer disease in residents of Vercelli (northern Italy), by analysing mortality data and hospital discharge forms. This was done in order to verify whether, as widely suspected among the city's population, an increased risk of cancer exists in the area, due to the large number of existing agricultural and industrial activities. Tumour mortality rates were compared with mortality data from the tumour registries of the province of Biella and of the city of Turin to identify a possible excess number of cases in Vercelli.An increased mortality rate was observed with respect to reference values (mortality registry of the city of Turin) for several tumours; more specifically results revealed a significantly increased mortality rate due to colorectal tumours, leukemias and nervous system tumours in both genders. Excess mortality was detected in males but not in females for esophageal cancer, non melanoma skin cancers, pancreatic, laryngeal, prostatic, renal and bone cancers. Conversely, in females, the standard mortality ratios (SMR) were found to be statistically significant for renal and laryngeal cancers and for Hodgkin's lymphoma.
本研究的主要目的是通过分析死亡率数据和医院出院表格，评估意大利北部韦尔切利居民的癌症疾病负担。这样做是为了验证，由于该地区存在大量农业和工业活动，正如该市居民普遍怀疑的那样，该地区是否存在癌症风险增加的情况。将肿瘤死亡率与比耶拉省和都灵市肿瘤登记处的死亡率数据进行比较，以确定韦尔切利可能存在的病例过多情况。观察到几种肿瘤的死亡率相对于参考值（都灵市死亡率登记处）有所增加；更具体地说，结果显示，结直肠癌、白血病和神经系统肿瘤导致的男女死亡率均显著增加。在男性中检测到食管癌、非黑色素瘤皮肤癌、胰腺癌、喉癌、前列腺癌、肾癌和骨癌的超额死亡率，但女性未检测到。相反，在女性中，发现肾癌、喉癌和霍奇金淋巴瘤的标准化死亡率（SMR）具有统计学意义。
