• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

[一家乡村医院遵循临床指南对成人社区获得性肺炎的管理]

[Management of community acquired pneumonia in adults following clinical guidelines at a rural hospital].

作者信息

Sanhueza A Luis Manuel, Vásquez P Cristián, Sepúlveda Z Fabiola, Barahona C Francisca, González C Rubén, Saldías P Fernando

机构信息

Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.

出版信息

Rev Med Chil. 2009 Oct;137(10):1283-90.

PMID:20011934
Abstract

BACKGROUND

A National Consensus Guideline published in 2005 established the basis for the diagnostic, severity assessment and treatment of community acquired pneumonia (CAP) in the adult population. The compliance with pneumonia clinical guidelines has been associated to a reduction in hospital stay healthcare-related costs, morbidity and mortality.

AIM

To describe the management and outcome of non-severe CAP in hospitalized adult patients treated in a rural hospital, based on the national clinical guidelines.

PATIENTS AND METHODS

Ninety six patients aged 74 +/- 13 years (50 males) hospitalized with non-severe pneumonia (group 3) at a community-based primary care center between January 1, 2006, and March 31, 2007, were evaluated.

RESULTS

Eighty percent of patients had concomitant diseases such as hypertension in 49%, diabetes in 23% and chronic obstructive pulmonary disease in 18%. All were treated with a third generation cephalosporin (ceftriaxone 1-2 g/day TV) as empirical therapy. Only 9% of patients also received a macrolide. Early switch to oral antimicrobial therapy was successful in two third of cases. Mean hospital length of stay was 5.0 +/- 2.5 days, and 30-day mortality was 6.3%.

CONCLUSIONS

Following the recommendations of the national clinical guidelines, most of these patients had a favorable response to monotherapy with a beta-lactam antimicrobial. Early switch therapy to oral antibiotic was effective and safe, reducing significantly hospital length of stay as compared to previous national clinical studies.

摘要

背景

2005年发布的一项全国性共识指南为成人社区获得性肺炎(CAP)的诊断、严重程度评估和治疗奠定了基础。遵循肺炎临床指南与缩短住院时间、降低医疗相关成本、发病率和死亡率相关。

目的

基于国家临床指南,描述在一家乡村医院接受治疗的住院成年非重症CAP患者的管理和结局。

患者与方法

对2006年1月1日至2007年3月31日期间在一家社区基层医疗中心因非重症肺炎住院的96例年龄为74±13岁(50例男性)的患者进行了评估。

结果

80%的患者患有合并症,如49%患有高血压,23%患有糖尿病,18%患有慢性阻塞性肺疾病。所有患者均接受第三代头孢菌素(头孢曲松1 - 2 g/天静脉滴注)作为经验性治疗。只有9%的患者还接受了大环内酯类药物治疗。三分之二的病例成功早期转换为口服抗菌治疗。平均住院时间为5.0±2.5天,30天死亡率为6.3%。

结论

遵循国家临床指南的建议,这些患者中的大多数对β-内酰胺类抗菌药物单药治疗反应良好。早期转换为口服抗生素治疗有效且安全,与之前的国家临床研究相比,显著缩短了住院时间。

相似文献

1
[Management of community acquired pneumonia in adults following clinical guidelines at a rural hospital].[一家乡村医院遵循临床指南对成人社区获得性肺炎的管理]
Rev Med Chil. 2009 Oct;137(10):1283-90.
2
Antimicrobial selection for hospitalized patients with presumed community-acquired pneumonia: a survey of nonteaching US community hospitals.对疑似社区获得性肺炎的住院患者进行抗菌药物选择:美国非教学型社区医院的一项调查
Ann Pharmacother. 2000 Apr;34(4):446-52. doi: 10.1345/aph.19174.
3
Guideline-concordant antibiotic use and survival among patients with community-acquired pneumonia admitted to the intensive care unit.指南一致的抗生素使用与 ICU 收治的社区获得性肺炎患者的生存。
Clin Ther. 2010 Feb;32(2):293-9. doi: 10.1016/j.clinthera.2010.02.006.
4
Safety and efficacy of CURB65-guided antibiotic therapy in community-acquired pneumonia.CURB65 指导下的抗生素治疗在社区获得性肺炎中的安全性和疗效。
J Antimicrob Chemother. 2011 Feb;66(2):416-23. doi: 10.1093/jac/dkq426. Epub 2010 Nov 16.
5
Improving outcomes in elderly patients with community-acquired pneumonia by adhering to national guidelines: Community-Acquired Pneumonia Organization International cohort study results.通过遵循国家指南改善老年社区获得性肺炎患者的治疗效果:社区获得性肺炎组织国际队列研究结果
Arch Intern Med. 2009 Sep 14;169(16):1515-24. doi: 10.1001/archinternmed.2009.265.
6
Inpatient care of community-acquired pneumonia: the effect of antimicrobial guidelines on clinical outcomes and drug costs in Canadian teaching hospitals.社区获得性肺炎的住院治疗:抗菌药物指南对加拿大教学医院临床结局和药物成本的影响。
Can Respir J. 2004 Mar;11(2):131-7. doi: 10.1155/2004/970828.
7
Empiric treatment in hospitalized community-acquired pneumonia. Impact on mortality, length of stay and re-admission.住院社区获得性肺炎的经验性治疗。对死亡率、住院时间和再入院的影响。
Respir Med. 2007 Sep;101(9):1909-15. doi: 10.1016/j.rmed.2007.04.018. Epub 2007 Jul 12.
8
Impact of guideline-concordant empiric antibiotic therapy in community-acquired pneumonia.指南一致的经验性抗生素治疗对社区获得性肺炎的影响
Am J Med. 2006 Oct;119(10):865-71. doi: 10.1016/j.amjmed.2006.02.014.
9
Adherence to guidelines for hospitalized community-acquired pneumonia over time and its impact on health outcomes and mortality.随着时间推移对住院社区获得性肺炎指南的遵循情况及其对健康结局和死亡率的影响。
Intern Emerg Med. 2016 Oct;11(7):929-40. doi: 10.1007/s11739-016-1445-3. Epub 2016 Apr 20.
10
Guideline-concordant therapy and reduced mortality and length of stay in adults with community-acquired pneumonia: playing by the rules.符合指南的治疗与社区获得性肺炎成人患者死亡率降低及住院时间缩短:依规行事。
Arch Intern Med. 2009 Sep 14;169(16):1525-31. doi: 10.1001/archinternmed.2009.259.