Tajouri Tanya H, Chareonthaitawee Panithaya
Department of Internal Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.
Expert Rev Cardiovasc Ther. 2010 Jan;8(1):55-63. doi: 10.1586/erc.09.157.
The high rate of periprocedural morbidity and mortality associated with revascularization in moderate-to-severe left ventricular systolic dysfunction has provided the rationale for noninvasive viability imaging. The most established viability imaging techniques are PET, single-photon emission computed tomography and dobutamine echocardiography. Cardiac MRI is gaining widespread use and accessibility, and computed tomography is emerging as a promising technique. Each imaging modality has unique advantages but also suffers from limitations. Furthermore, evidence of the impact of viability imaging on patient outcomes has generally been limited to observational studies. Uncertainty remains regarding the optimal treatment strategy in this patient subset. This review describes the current status of viability imaging and revascularization in chronic moderate-to-severe ischemic left ventricular systolic dysfunction.
在中重度左心室收缩功能障碍患者中，血管重建术相关的围手术期发病率和死亡率较高，这为无创性存活心肌成像提供了理论依据。最成熟的存活心肌成像技术是正电子发射断层扫描（PET）、单光子发射计算机断层扫描和多巴酚丁胺超声心动图。心脏磁共振成像（MRI）的应用越来越广泛且容易获得，计算机断层扫描正成为一种有前景的技术。每种成像方式都有其独特的优势，但也存在局限性。此外，存活心肌成像对患者预后影响的证据通常仅限于观察性研究。对于这一患者亚组的最佳治疗策略仍存在不确定性。本综述描述了慢性中重度缺血性左心室收缩功能障碍患者存活心肌成像和血管重建术的现状。
