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肥厚型心肌病的心脏磁共振成像:当前技术水平

Cardiac magnetic resonance in hypertrophic cardiomyopathy: current state of the art.

作者信息

Kwon Deborah H, Desai Milind Y

机构信息

Heart and Vascular Institute, Cleveland Clinic, Cleveland, OH 44195, USA.

出版信息

Expert Rev Cardiovasc Ther. 2010 Jan;8(1):103-11. doi: 10.1586/erc.09.108.

Abstract

Hypertrophic cardiomyopathy is a complex disorder with significant heterogeneity in clinical characteristics and natural history. Traditionally, the diagnosis has been based on clinical assessment and echocardiography; however, persistent challenges in its noninvasive evaluation remain. Hence, improved diagnostic techniques could lead to better risk stratification of patients, which would potentially identify patients likely to benefit from effective therapies. Recent studies have demonstrated the increasing utility of cardiac magnetic resonance in the management of this disease. With the increasing utilization of genetics, cardiac magnetic resonance is likely to play an even more important role in discerning the subtle morphologic differences seen in such patients with similar genotypic profiles.

摘要

肥厚型心肌病是一种复杂的疾病,在临床特征和自然病史方面具有显著的异质性。传统上,诊断基于临床评估和超声心动图;然而,其无创评估仍存在持续挑战。因此,改进的诊断技术可能会使患者的风险分层更完善,这有可能识别出可能从有效治疗中获益的患者。最近的研究表明,心脏磁共振成像在该疾病的管理中越来越有用。随着遗传学应用的增加,心脏磁共振成像在辨别具有相似基因型特征的此类患者中所见到的细微形态学差异方面可能会发挥更重要的作用。

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