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Novel detection system for plant protein production of pharmaceuticals and impact on conformational diseases.

作者信息

Nagel K A, Kastenholz B, Gilmer F, Schurr U, Walter A

机构信息

Institute of Chemistry and Dynamics of the Geosphere ICG-3: Phytosphere, Forschungszentrum Jülich GmbH, 52425 Jülich, Germany.

出版信息

Protein Pept Lett. 2010 Jun;17(6):723-31. doi: 10.2174/092986610791190282.

Abstract

tate-of-the-art biochemistry methods in combination with an automated phenotyping method demonstrate the high potential of transgenic tobacco plants in producing properly-folded therapeutic proteins for the treatment of protein-misfolding diseases (e.g., Alzheimer's disease). This molecular farming approach led to highest protein production of hydroponically-grown tobacco compared to other growth substrates generally used in plant cultivation.

摘要

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