Nagasue N, Inokuchi K, Kobayashi M, Saku M, Iwaki A
Am J Surg. 1977 Nov;134(5):650-5. doi: 10.1016/0002-9610(77)90456-1.
Complete dearterialization of the entire liver was carried out in three patients with nonresectable liver cell carcinoma in whom the right or left portal vein had already obstructed due to tumor thrombosis or invasion. Although remittent fever ensued for two to three weeks postoperatively in all patients, hepatic infaction never occurred in the devascularized hepatic lobes. The effect of the treatment on tumorous lesions appeared satisfactory. The results indicated that the tumor-bearing liver can tolerate nearly complete deprivation of hepatic arterial and portal blood in at least one lobe of the liver if it is not simultaneous.
对3例无法切除的肝细胞癌患者进行了全肝完全去动脉化，这些患者的右或左门静脉已因肿瘤血栓形成或侵犯而阻塞。尽管所有患者术后两到三周都出现了弛张热，但去血管化的肝叶从未发生肝梗死。该治疗对肿瘤病变的效果似乎令人满意。结果表明，如果不是同时进行，荷瘤肝脏至少在一个肝叶中能够耐受几乎完全剥夺肝动脉和门静脉血供。
