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主观认知障碍和轻度认知障碍中的人格特征——痴呆的早期指标?

Personality features in subjective cognitive impairment and mild cognitive impairment--early indicators of dementia?

机构信息

Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm University, Stockholm, Sweden.

出版信息

Dement Geriatr Cogn Disord. 2009;28(6):528-35. doi: 10.1159/000255104. Epub 2009 Dec 10.

DOI:10.1159/000255104
PMID:20016183
Abstract

OBJECTIVES

The purpose of the present study was to investigate patterns of personality in patients with subjective cognitive impairment (SCI) and mild cognitive impairment (MCI), compared to healthy controls.

METHODS

We assessed24 patients with SCI, 35 patients with MCI and 26 healthy controls with the self-report questionnaire Swedish Universities Scales of Personality measuring aspects of neuroticism/anxiety proneness, extraversion, and aggression-hostility.

RESULTS

Patients with SCI and MCI showed significantly more Somatic Trait Anxiety, Psychic Trait Anxiety and Stress Susceptibility than healthy controls. Moreover, there was a significant increase in Detachment in patients with MCI and a significant decrease in Adventure Seeking in patients with SCI, relative to healthy controls.

CONCLUSIONS

Patients with SCI and MCI presented specific patterns of personality alterations with higher scores in traits related to anxiety proneness and aggression-hostility and lower in traits of extraversion. In most subscales differences followed a sequential pattern with gradually increasing scores from healthy controls, to patients with SCI and further to MCI. The groups differed in amount and type of symptoms, suggesting that patterns of personality may be related to degree of cognitive impairment.

摘要

目的

本研究旨在探讨主观认知障碍(SCI)和轻度认知障碍(MCI)患者的人格模式,并与健康对照组进行比较。

方法

我们使用瑞典大学人格量表(Swedish Universities Scales of Personality)对 24 名 SCI 患者、35 名 MCI 患者和 26 名健康对照组进行了自我报告问卷调查,该量表评估了神经质/焦虑倾向、外向性和攻击性/敌意等方面。

结果

与健康对照组相比,SCI 和 MCI 患者的躯体特质焦虑、精神特质焦虑和应激易感性显著更高。此外,MCI 患者的超脱得分显著增加,SCI 患者的冒险寻求得分显著降低。

结论

SCI 和 MCI 患者表现出特定的人格改变模式,与焦虑倾向和攻击性/敌意相关的特质得分较高,而与外向性相关的特质得分较低。在大多数子量表中,差异呈现出从健康对照组、SCI 患者到 MCI 患者逐渐增加的顺序模式。这些组在症状的数量和类型上存在差异,表明人格模式可能与认知障碍的程度有关。

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