Hahlin M, Sjöblom P, Lindblom B
Department of Obstetrics and Gynecology, University of Göteborg, Sahlgrenska University Hospital, Sweden.
Fertil Steril. 1991 Mar;55(3):492-6. doi: 10.1016/s0015-0282(16)54173-9.
Progesterone (P) level and daily change in human chorionic gonadotropin (hCG) were determined in the serum of 307 patients with suspected ectopic pregnancy (EP). Of the viable intrauterine pregnancies (IUP), 99% had P values above 30 nmol/L, whereas 75% of the EP and 81% of the spontaneous abortions had P values less than 30 nmol/L. Among the viable IUP, 95% had normal hCG increases, whereas 89% of the EP and 99% of the spontaneous abortions had abnormal hCG increases. A P value less than 30 nmol/L combined with an abnormal hCG increase had a positive predictive value for pathological pregnancy of 1.0. Consequently, in such cases, further invasive diagnostic or therapeutic measures can be taken with a low risk of jeopardizing a viable IUP.
对307例疑似异位妊娠（EP）患者的血清进行了孕酮（P）水平及人绒毛膜促性腺激素（hCG）每日变化情况的测定。在存活的宫内妊娠（IUP）中，99%的患者P值高于30 nmol/L，而75%的异位妊娠患者和81%的自然流产患者P值低于30 nmol/L。在存活的宫内妊娠中，95%的患者hCG呈正常升高，而89%的异位妊娠患者和99%的自然流产患者hCG呈异常升高。P值低于30 nmol/L且hCG升高异常对病理性妊娠的阳性预测值为1.0。因此，在这种情况下，可以采取进一步的侵入性诊断或治疗措施，而危及存活宫内妊娠的风险较低。
