酸雨致死：VAP 还是 EXIT？
Death by acid rain: VAP or EXIT?
机构信息
Department of Paediatric Intensive Care, Royal Liverpool Children's Hospital - Alder Hey, Liverpool, L12 2AP, UK.
出版信息
Crit Care. 2009;13(6):1008. doi: 10.1186/cc8169. Epub 2009 Nov 2.
Abstract
Ventilator-associated pneumonia (VAP) is a new (nosocomial) lower respiratory tract infection diagnosed in mechanically ventilated patients 48 or more hours after intubation. There is no gold standard for establishing the diagnosis and its pathogenesis is iatrogenic and multifactorial. Gastro-oesophageal reflux is common in mechanically ventilated children, but its role in VAP remains speculative. VAP is associated with increased mortality and morbidity, prolonged duration of ventilation and hospital stay, and escalated costs of hospitalisation. VAP 'bundles' are championed as the antidote.
摘要
呼吸机相关性肺炎（VAP）是指机械通气患者在插管后 48 小时或更长时间发生的新（医院获得性）下呼吸道感染。目前尚无诊断 VAP 的金标准，其发病机制是医源性和多因素的。机械通气患儿中胃食管反流很常见，但在 VAP 中的作用仍存在推测。VAP 与死亡率和发病率增加、通气时间和住院时间延长以及住院费用增加有关。VAP“套餐”被认为是一种解毒剂。
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