Korea University Hospital, Seoul, Republic of Korea.
J Urol. 2010 Feb;183(2):603-7. doi: 10.1016/j.juro.2009.10.016. Epub 2009 Dec 16.
We prospectively evaluated magnetic resonance urethrography for depicting obliterative posterior urethral stricture.
A total of 25 men with a mean age of 48.7 years (range 21 to 72) with complete posterior urethral stricture were studied preoperatively with axial and sagittal turbo spin-echo T2, sagittal T1 and contrast enhanced sagittal T1-weighted images. Of the 25 patients 22 underwent conventional retrograde urethrography with voiding cystourethrography. For magnetic resonance urethrography aseptic lubricant was infused through the external urethral meatus to dilate the distal urethra up to the stricture. Each imaging result was compared with a surgical specimen or a description of the surgical findings. Measurement errors were analyzed using the Wilcoxon signed rank test. The relationship between true and measured stricture length was evaluated by linear regression analysis.
Based on magnetic resonance urethrography findings 2 patients with a less than 1 cm stricture were treated with internal urethrotomy, 21 with a more than 1 cm stricture underwent open urethroplasty and 2 with prostatic displacement and a 4 cm stricture needed the combined perineal and transpubic approach. The mean +/- SD measurement error on magnetic resonance urethrography imaging was significantly lower than that on conventional retrograde urethrography combined with voiding cystourethrography (0.4 +/- 0.4 vs 1.4 +/- 1.1 cm, p <0.001). Linear regression analysis showed a stronger linear relationship between magnetic resonance urethrography and surgical measurement (r(2) = 0.62, p <0.01).
Magnetic resonance urethrography is more effective for evaluating obliterative posterior urethral stricture than retrograde urethrography combined with voiding cystourethrography.
我们前瞻性地评估磁共振尿道造影在描绘闭塞性后尿道狭窄中的作用。
共 25 名男性患者,平均年龄 48.7 岁(范围 21 至 72 岁),均患有完全性后尿道狭窄。术前分别行轴位和矢状位涡轮自旋回波 T2、矢状位 T1 和对比增强矢状位 T1 加权成像。25 例患者中,22 例行常规逆行尿道造影联合排尿性膀胱尿道造影。对于磁共振尿道造影,通过尿道外口注入无菌润滑剂,将远端尿道扩张至狭窄处。比较每个成像结果与手术标本或手术发现的描述。使用 Wilcoxon 符号秩检验分析测量误差。通过线性回归分析评估真实和测量狭窄长度之间的关系。
根据磁共振尿道造影结果,2 例狭窄小于 1cm 的患者接受了尿道内切开术,21 例狭窄大于 1cm 的患者接受了开放尿道成形术,2 例前列腺移位和 4cm 狭窄的患者需要会阴和经耻骨联合联合入路。磁共振尿道造影成像的平均 +/-SD 测量误差明显低于逆行尿道造影联合排尿性膀胱尿道造影(0.4 +/- 0.4 比 1.4 +/- 1.1cm,p <0.001)。线性回归分析显示磁共振尿道造影与手术测量之间具有更强的线性关系(r(2) = 0.62,p <0.01)。
磁共振尿道造影比逆行尿道造影联合排尿性膀胱尿道造影更有效地评估闭塞性后尿道狭窄。