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尿道支架失败的处理-复发性前尿道狭窄。

Management of urethral stent failure for recurrent anterior urethral strictures.

机构信息

Centre for Reconstructive Urethral and Genitalia Surgery, Arezzo, Italy.

出版信息

Eur Urol. 2010 Apr;57(4):615-21. doi: 10.1016/j.eururo.2009.11.038. Epub 2009 Dec 1.

Abstract

BACKGROUND

Urethral stent placement for recurrent anterior urethral strictures may cause restenosis and complications.

OBJECTIVE

To describe our experience with patients who had restenoses and complications following urethral stent placement for the treatment of recurrent anterior urethral strictures.

DESIGN, SETTING, AND PARTICIPANTS: We evaluated retrospectively the records of 13 men with anterior urethral stricture who experienced restenosis and complications after stent insertion. We recorded stent position, prestent and poststent urethral procedures, restenosis location, stent-related complications, and management of stent failures.

SURGICAL PROCEDURE

The stent was removed en bloc with the whole strictured urethral segment or wire by wire after a ventral or a double-ventral plus dorsal-sagittal urethrotomy and stent section.

MEASUREMENTS

Successful outcome was defined as standard voiding, without need of any postoperative procedure, and full recovery from complications.

RESULTS AND LIMITATIONS

Four patients did not undergo surgery and the stent was left in situ. Of these patients, two required permanent suprapubic cystostomy. Nine patients underwent challenging surgical stent removal and salvage urethrostomy: After the first stage, three patients are waiting for further reconstructive steps, five elected the urethrostomy as a permanent diversion, and one completed the staged reconstruction using a buccal mucosa graft at the second stage. After surgery, seven of the nine patients (77.8%) were free of strictures and stent-related complications, while a restenosis occurred in two of the nine (22.2%) cases.

CONCLUSIONS

The management of urethral stent failure represents a therapeutic challenge. The stent risks converting a simple stenosis into a complex stenosis requiring a staged urethroplasty, a definitive urethrostomy, or a permanent suprapubic diversion.

摘要

背景

尿道支架置入治疗复发性前尿道狭窄可能导致再狭窄和并发症。

目的

描述我们在尿道支架置入治疗复发性前尿道狭窄后出现再狭窄和并发症的患者的经验。

设计、设置和参与者:我们回顾性评估了 13 名前尿道狭窄男性患者的病历,这些患者在支架置入后出现再狭窄和并发症。我们记录了支架位置、支架置入前后的尿道操作、再狭窄部位、支架相关并发症以及支架失败的处理。

手术步骤

在经腹或双腹-背矢状切开尿道吻合术和支架分段后,整块取出支架和整个狭窄尿道段或用线取出支架。

测量

成功结果定义为标准排尿,无需任何术后处理,且并发症完全恢复。

结果和局限性

4 名患者未行手术,支架仍留在原位。其中 2 例患者需要永久性耻骨上膀胱造口术。9 名患者行有挑战性的手术支架取出和挽救性尿道吻合术:第一阶段后,3 名患者等待进一步的重建步骤,5 名患者选择尿道吻合术作为永久性引流,1 名患者在第二阶段使用颊黏膜移植物完成分期重建。手术后,9 名患者中有 7 名(77.8%)无狭窄和支架相关并发症,9 名中有 2 名(22.2%)发生再狭窄。

结论

尿道支架失败的处理是一个治疗挑战。支架有将简单狭窄转化为需要分期尿道成形术、确定性尿道造口术或永久性耻骨上分流术的复杂狭窄的风险。

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