Nationwide Children's Hospital, Columbus, OH, USA.
Pediatr Radiol. 2010 May;40(5):714-9. doi: 10.1007/s00247-009-1484-2. Epub 2009 Dec 18.
Eosinophilic esophagitis is increasingly recognized as a cause of dysphagia or food impaction in pediatric patients. It has a high male predominance and is often associated with a history of allergy or asthma.
To correlate fluoroscopic findings in eosinophilic esophagitis with the endoscopic and histologic findings.
We retrospectively reviewed the upper gastrointestinal (UGI) findings of eosinophilic esophagitis and correlated them with the clinical, endoscopic and histologic findings in a series of 17 children (12 boys, 5 girls).
UGI findings were normal in 12 children, including 4 who had a normal UGI exam after endoscopic disimpaction for an obstructing food bolus. Five children had strictures identified on UGI: one was demonstrated with endoscopy. This suggests that the impactions and strictures were due to an esophageal dysmotility rather than a fixed anatomic abnormality.
Because the UGI findings are frequently normal in eosinophilic esophagitis, radiologists need to have a high index of suspicion for this disease. In children with a strong clinical history, especially impaction in the absence of an esophageal stricture, endoscopy and biopsy are indicated for further evaluation.
嗜酸性粒细胞性食管炎越来越被认为是小儿吞咽困难或食物嵌塞的原因。它具有很高的男性优势，并且常与过敏或哮喘史有关。
将嗜酸性粒细胞性食管炎的荧光镜检查结果与内镜和组织学检查结果相关联。
我们回顾性地分析了嗜酸性粒细胞性食管炎的上消化道（UGI）检查结果，并将其与一系列 17 名儿童（12 名男孩，5 名女孩）的临床、内镜和组织学检查结果进行了相关性分析。
12 名儿童的 UGI 检查结果正常，其中 4 名在因阻塞性食物团块而行内镜取石术后 UGI 检查正常。5 名儿童在 UGI 上发现了狭窄：其中 1 名经内镜证实。这表明嵌塞和狭窄是由于食管运动障碍引起的，而不是固定的解剖异常。
由于嗜酸性粒细胞性食管炎的 UGI 检查结果常常正常，放射科医生需要对此病保持高度怀疑。对于有强烈临床病史的儿童，特别是在没有食管狭窄的情况下发生嵌塞，应进行内镜检查和活检以进一步评估。
