Royal Victoria Hospital, Belfast, Northern Ireland, UK.
Rheumatol Int. 2012 Jan;32(1):249-51. doi: 10.1007/s00296-009-1322-8. Epub 2009 Dec 18.
Hyperimmunoglobulin D and periodic fever syndrome (HIDS) is a rare, hereditary autoinflammatory condition, characterized by recurrent inflammatory episodes. There is no proven treatment for HIDS, but various drugs including, non-steroidal anti-inflammatory drugs, colchicine, steroids, statins and thalidomide have all been tried. Recently, some patients have demonstrated a good clinical response to either etanercept or anakinra. We report a case of a 10-year-old girl who experienced prolonged and severe inflammatory attacks, when she was treated with etanercept, and later with anakinra.
高免疫球蛋白 D 伴周期性发热综合征（HIDS）是一种罕见的遗传性自身炎症性疾病，其特征为反复发作的炎症发作。目前尚无针对 HIDS 的有效治疗方法，但已尝试使用各种药物，包括非甾体抗炎药、秋水仙碱、类固醇、他汀类药物和沙利度胺。最近，一些患者对依那西普或阿那白滞素表现出良好的临床反应。我们报告了一例 10 岁女孩的病例，她在接受依那西普治疗后出现了长时间和严重的炎症发作，后来改用阿那白滞素。
