Boehm R, Stroh C, Blueher S, Till H, Wolff S, Manger T, Lippert H
Universitätsklinikum Leipzig AöR, Klinik und Poliklinik für Kinderchirurgie, Leipzig, Deutschland.
Zentralbl Chir. 2009 Dec;134(6):532-6. doi: 10.1055/s-0029-1224643. Epub 2009 Dec 17.
Obesity in childhood and adolescents has gained epidemic proportions; in Germany 15-20 % of boys and girls are overweight, more than 6 % are known to be obese. By now, 25 % of relevant people show a pathological glucose intolerance, 4-5 % are developing type 2 diabetes mellitus (T2DM). In addition, metabolic disorders leading to hypertension and cardiac, renal or ophthalmological complications could be named as serious comorbidities. Medical and behavioural intervention as treatment for obesity in childhood remains largely ineffective: 5-10 % weight loss within 2 years rarely results in significant durable success. In adults, bariatric surgery is being used increasingly as an effective approach to achieve weight loss and to improve serious medical comorbidities, in particular T2DM. Enhancement of quality of life and explicit extension of survival are concomitant phenomenons. To date, a range of different types of bariatric procedures has been performed in adolescents, but studies evaluating and analysing preoperative data, postoperative course and follow-up in a representative number of patients younger than 18 years are still lacking. Nevertheless, current experience suggests significant weight loss and improving obesity-related medical comorbidities after bariatric surgery in adolescents too. Moreover, bariatric surgery in adolescents seems to induce less complications and a shorter hospital stay than in adults. Al-though surgical therapy for obesity in this group of patients remains an individual decision, even though explicit guidelines have been published specifying inclusion and exclusion criterias. Analysis of our own patient group and results of the study of the quality assurance "surgical treatment of morbid obesity" are appropriate tools to evaluate surgical techniques and to provide long-term follow-up.
儿童和青少年肥胖已呈流行趋势;在德国,15%至20%的男孩和女孩超重,超过6%的人被认为肥胖。目前,25%的相关人群存在病理性糖耐量异常,4%至5%的人正在发展为2型糖尿病(T2DM)。此外,导致高血压以及心脏、肾脏或眼科并发症的代谢紊乱可被列为严重的合并症。作为儿童肥胖治疗方法的医学和行为干预在很大程度上仍然无效:两年内体重减轻5%至10%很少能取得显著持久的成功。在成年人中,减肥手术越来越多地被用作实现体重减轻和改善严重医学合并症(特别是T2DM)的有效方法。生活质量的提高和生存期的明显延长是相伴出现的现象。迄今为止,已经对青少年实施了一系列不同类型的减肥手术,但仍缺乏对大量18岁以下患者的术前数据、术后过程和随访进行评估和分析的研究。然而,目前的经验表明,减肥手术在青少年中也能显著减轻体重并改善与肥胖相关的医学合并症。此外,青少年减肥手术似乎比成年人引发的并发症更少,住院时间更短。尽管对这类患者实施手术治疗仍是一项个体化决定,尽管已经发布了明确的指南规定了纳入和排除标准。分析我们自己的患者群体以及质量保证“病态肥胖的手术治疗”研究结果是评估手术技术和提供长期随访的合适工具。
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