Graduate School of Biomedical Engineering, University of New South Wales, Sydney, NSW 2052, Australia.
Expert Rev Med Devices. 2010 Jan;7(1):35-49. doi: 10.1586/erd.09.58.
Bioelectrodes for neural recording and neurostimulation are an integral component of a number of neuroprosthetic devices, including the commercially available cochlear implant, and developmental devices, such as the bionic eye and brain-machine interfaces. Current electrode designs limit the application of such devices owing to suboptimal material properties that lead to minimal interaction with the target neural tissue and the formation of fibrotic capsules. In designing an ideal bioelectrode, a number of design criteria must be considered with respect to physical, mechanical, electrical and biological properties. Conducting polymers have the potential to address the synergistic interaction of these properties and show promise as superior coatings for next-generation electrodes in implant devices.
用于神经记录和神经刺激的生物电极是许多神经假体设备的一个组成部分，包括商业上可用的人工耳蜗植入物，以及发展中的设备，如仿生眼和脑机接口。当前的电极设计由于材料性能不理想而限制了这些设备的应用，导致与目标神经组织的相互作用最小，并形成纤维囊。在设计理想的生物电极时，必须考虑到物理、机械、电气和生物特性的一系列设计标准。导电聚合物具有解决这些特性协同作用的潜力，并有望成为植入式设备中下一代电极的优异涂层。
