Dubbeldam Jacob Leendert
Institute of Biology, Leiden University, Leiden, The Netherlands.
Cent Nerv Syst Agents Med Chem. 2009 Jun;9(2):150-8. doi: 10.2174/187152409788452072.
Aim of this paper is to give a concise overview of what is known about the trigeminal nociceptive system in birds. Several types of nociceptors have been discovered, thermal nociceptors and polymodal, i.e. mechanothermal and mechanochemical receptors. Information from these receptors reaches the Laminae I and II of the caudal subnucleus of the descending trigeminal system and of the dorsal horn of the rostral spinal cord. The organization of the afferents to the avian brainstem and of the primary nociceptive centers is largely the same as that in mammals. This is also true for a number of histochemical characteristics of these primary centers. The comparability of the ascending nociceptive system in birds and mammals is more problematic. This is due to the differences in organization of the forebrain in mammals and birds. The paper concludes with a short discussion on the sense of pain and the connection with nociception.
本文旨在简要概述鸟类三叉神经伤害感受系统的已知情况。已发现了几种类型的伤害感受器，即热伤害感受器和多模式感受器，也就是机械热感受器和机械化学感受器。来自这些感受器的信息到达三叉神经下行系统尾侧亚核的I层和II层以及延髓脊髓背角。传入鸟类脑干和初级伤害感受中枢的神经纤维组织在很大程度上与哺乳动物相同。这些初级中枢的一些组织化学特征也是如此。鸟类和哺乳动物上行伤害感受系统的可比性则更成问题。这是由于哺乳动物和鸟类前脑组织结构的差异所致。本文最后简短讨论了痛觉以及与伤害感受的联系。
