He Yu, Li Zhi-hua, Cai Jing-xiu, Han Ben-li, He Zhen-ping, Wang Shu-guang, Bie Ping
Institute of Hepatobiliary Surgery, Southwest Hospital, Third Military Medical University, Chongqing 400038, China.
Zhonghua Wai Ke Za Zhi. 2009 Aug 1;47(15):1151-4.
To investigate the surgical treatment for hilar cholangiocarcinoma(HCCA) of Bismuth-Corlette type IV.
The clinical data of 73 HCCA patients admitted in Southwest Hospital, the Third Military Medical University from January 2002 to December 2008 were analyzed retrospectively. There were 41 males and 32 females, aged from 30 to 84 years old (averaged, 56.8 years old). All patients were diagnosed as hilar mass with hilar biliary obstruction by B-ultrasound, CT, magnetic resonance imaging, endoscopic retrograde cholangiopancreatography, magnetic resonance cholangiopancreatography or percutaneous transhepatic cholangiography, and confirmed by pathological examination in intra-operation and post-operation. Diagnosis of all patients were according to Bismuth-Corlette type IV.
Fifteen cases underwent percutaneous transhepatic cholangial drainage, stents were implanted in 8 patients. Simple internal drainage was performed on 25 of the 73 patients and 4 with palliative resection. Radical resection was performed on 19 patients. The radical resection rate of HCCA were 26.0%. The 1, 3 years of survival rates were 36.8%, 10.5% respectively. The 1 year survival rate was 6.3% in drainage group.
Radical resection is the potentially curative treatment for HCCA, a sufficient, reasonable use of internal and external drainage would improve the patient's quality of life.
探讨IV型肝门部胆管癌(HCCA)的手术治疗方法。
回顾性分析2002年1月至2008年12月第三军医大学西南医院收治的73例HCCA患者的临床资料。其中男性41例,女性32例,年龄30~84岁,平均56.8岁。所有患者均经B超、CT、磁共振成像、内镜逆行胰胆管造影、磁共振胰胆管造影或经皮肝穿刺胆管造影检查诊断为肝门部肿块伴肝门部胆管梗阻,并经术中及术后病理检查证实。所有患者诊断均符合Bismuth-Corlette IV型。
15例行经皮肝穿刺胆管引流术,8例植入支架。73例患者中25例行单纯内引流术,4例行姑息性切除术。19例行根治性切除术。HCCA的根治性切除率为26.0%。1、3年生存率分别为36.8%、10.5%。引流组1年生存率为6.3%。
根治性切除是HCCA可能的治愈性治疗方法,充分、合理地应用内、外引流可提高患者生活质量。