Cervelli Valerio, De Angelis Barbara, Balzani Alberto, Colicchia Gianfranco, Spallone Diana, Grimaldi Monica
Department of Plastic and Reconstructive Surgery, Policlinico Casilino, University of Tor Vergata, Rome, Italy.
Acta Dermatovenerol Croat. 2009;17(4):273-8.
The aim of our study was to analyze the results obtained with the ReCell system for surgical treatment of stable vitiligo. At Department of Plastic and Reconstructive surgery, University of Tor Vergata in Rome, we treated 15 patients with stable vitiligo during a 2-year period. The stability of vitiligo lesions varied between 1 and 4 years. The mean stability was 2.25. The disease activity according to Vitiligo Disease Activity Score (VIDA) was 0 in all cases, which means that all patients had a stability of greater than or equal to 1 year. Three (20%) patients had vitiligo vulgaris, seven (46.6%) segmental vitiligo and five (33.3%) focal vitiligo. Repigmentation was assessed using the Vitiligo Area Scoring Index (VASI). The extent of pigmentation was scored as excellent, good, fair, and poor depending on the percentage of repigmentation in the previously depigmented site. The color of the repigmented area was compared with the adjacent normally pigmented area: excellent color match was present in ten (66.6%) and good in five (33.3%) cases. There was no fair or poor outcome. Repigmentation greater than 75% was recorded in 12 (80%) and 25% to 50% repigmentation in three (20%) of 15 patients treated. ReCell is a feasible, simple and safe technique. The method that uses noncultured autologous epidermal suspension is simpler, less expensive, less time consuming, and does not require sophisticated laboratory facilities as compared with the methods employing cultured melanocytes.
我们研究的目的是分析使用ReCell系统手术治疗稳定期白癜风的结果。在罗马第二大学整形与重建外科，我们在两年时间里治疗了15例稳定期白癜风患者。白癜风皮损的稳定期在1至4年之间，平均稳定期为2.25年。根据白癜风疾病活动评分（VIDA），所有病例的疾病活动度均为0，这意味着所有患者的稳定期均大于或等于1年。其中3例（20%）为寻常型白癜风，7例（46.6%）为节段型白癜风，5例（33.3%）为局限性白癜风。使用白癜风面积评分指数（VASI）评估色素再生情况。根据先前色素脱失部位的色素再生百分比，将色素沉着程度评为优、良、中、差。将色素再生区域的颜色与相邻正常色素沉着区域进行比较：10例（66.6%）颜色匹配优秀，5例（33.3%）颜色匹配良好，无中等或差的结果。15例接受治疗的患者中，12例（80%）色素再生大于75%，3例（20%）色素再生为25%至50%。ReCell是一种可行、简单且安全的技术。与采用培养黑素细胞的方法相比，使用非培养自体表皮悬液的方法更简单、成本更低、耗时更少，且不需要复杂的实验室设施。
