Furtado Mariana V, Cardoso Alíssia, Patrício Marcelo C, Rossini Ana Paula W, Campani Raquel B, Meotti Carolina, Nasi Luiz Antônio, Polanczyk Carísi Anne
Graduate Program in Cardiology, Federal University of Rio Grande do Sul, Porto Alegre, Brazil.
J Emerg Med. 2011 May;40(5):557-64. doi: 10.1016/j.jemermed.2009.08.062. Epub 2009 Dec 21.
Different strategies have been described to increase promptness and efficiency in the assessment and management of patients with acute chest pain and acute coronary syndrome (ACS) in the emergency department (ED).
The objective of this study is to evaluate the results of implementing a Chest Pain Unit (CPU) to assist patients with ACS, and to determine its impact on quality of health care indexes and clinical outcomes.
A study was conducted with a prospective cohort of patients admitted to the ED with a chief complaint of acute chest pain or suspected ACS at two different time periods: before (n = 663) and after (n = 450) introducing a CPU as part of the ED. Quality-of-care indexes analyzed in this study were adherence to a critical pathway, length of hospital stay, and hospital mortality.
There was increased adherence to a critical pathway during the CPU period compared to the period with no designated CPU area, including compliance with prescribing aspirin, beta-blockers, and angiotensin-converting enzyme inhibitor, and performing coronary angiography in high-risk patients. After adjustment to baseline characteristics, admissions to a CPU resulted in a 65% reduction in mortality (odds ratio 0.35; 95% confidence interval 0.14-0.88; p = 0.03). There was no difference in median length of hospital stay, 7 days (interquartile range [IQR] 4-12) before CPU and 6 days (IQR 4-11) after introducing the CPU (p = 0.10).
In the scenario of a crowded ED, implementation of a CPU was associated with greater adherence to a critical pathway for patients with ACS, with a concomitant reduction in mortality rates.
已有多种不同策略用于提高急诊科对急性胸痛和急性冠脉综合征(ACS)患者评估及管理的及时性和效率。
本研究旨在评估设立胸痛单元(CPU)辅助ACS患者的效果,并确定其对医疗质量指标和临床结局的影响。
对在两个不同时间段因急性胸痛为主诉或疑似ACS入住急诊科的患者进行前瞻性队列研究:引入CPU作为急诊科一部分之前(n = 663)和之后(n = 450)。本研究分析的医疗质量指标包括对关键路径的依从性、住院时间和医院死亡率。
与未设专门CPU区域的时期相比,在CPU时期对关键路径的依从性有所提高,包括阿司匹林、β受体阻滞剂和血管紧张素转换酶抑制剂的处方依从性,以及高危患者进行冠状动脉造影的情况。在对基线特征进行调整后,入住CPU的患者死亡率降低了65%(优势比0.35;95%置信区间0.14 - 0.88;p = 0.03)。住院时间中位数无差异,引入CPU前为7天(四分位间距[IQR] 4 - 12),引入后为6天(IQR 4 - 11)(p = 0.10)。
在急诊科拥挤的情况下,设立CPU与ACS患者对关键路径的更高依从性相关,同时死亡率降低。