Department of Obstetrics, Gynecology, and Reproductive Science, Mount Sinai School of Medicine, New York, NY, USA.
Am J Obstet Gynecol. 2010 Mar;202(3):276.e1-3. doi: 10.1016/j.ajog.2009.10.860. Epub 2009 Dec 22.
The objective of the study was to estimate whether surgical lubricant used during pelvic examination alters the detection of group B Streptococcus (GBS).
We conducted a prospective cohort study of patients undergoing GBS screening at the prenatal clinics of a New York City public hospital. Two specimens were collected from each patient, before and after a pelvic examination with Surgilube (Fougera and Co, Melville, NY), a bacteriostatic surgical lubricant. Test performance indices using GBS status pre-pelvic examination as the reference were calculated.
Over 10 months, 168 patients were enrolled in the study. Twenty of 168 patients (11.9%; 95% confidence interval, 7.4-17.8%) tested GBS positive before the pelvic examination. Of the initial 20 GBS-positive patients, 10 tested GBS positive after the pelvic examination with surgical lubricant. The sensitivity of detecting GBS after the examination with surgical lubricant was 50%.
Because pelvic examination with surgical lubricant may decrease the detection of GBS, obstetric practitioners should collect GBS screening cultures before the use of surgical lubricant.
本研究旨在评估在盆腔检查中使用外科润滑剂是否会改变 B 组链球菌(GBS)的检出率。
我们对在纽约市一家公立医院的产前诊所进行 GBS 筛查的患者进行了一项前瞻性队列研究。每位患者在使用 Surgilube(Fougera and Co,Melville,NY)进行盆腔检查前后采集两份标本,Surgilube 是一种抑菌性外科润滑剂。使用盆腔检查前的 GBS 状态作为参考,计算了检测性能指标。
在 10 个月的时间里,共有 168 名患者入组研究。在盆腔检查前,168 名患者中有 20 名(11.9%;95%置信区间,7.4-17.8%)检测出 GBS 阳性。在最初的 20 名 GBS 阳性患者中,有 10 名在使用外科润滑剂进行盆腔检查后 GBS 检测呈阳性。使用外科润滑剂进行检查后检测 GBS 的敏感性为 50%。
由于外科润滑剂的盆腔检查可能会降低 GBS 的检出率,产科医生应在使用外科润滑剂前采集 GBS 筛查培养物。