Wei Chi-Feng, She Bo-Ching, Liang Hung-Shuo, Ling Qing-Dong, Tsai Chen-Yuan, Yen Chih-Wei, Wu Hsueh-Yin, Tsai Ming-Song
Department of Obstetrics and Gynecology, Cathay General Hospital, Si-Jhih, Taiwan.
Taiwan J Obstet Gynecol. 2009 Jun;48(2):116-9. doi: 10.1016/S1028-4559(09)60269-2.
The aim of this study was to evaluate the percentage of pregnant women with negative Group B Streptococcus (GBS) screening results by culture at 35 weeks' gestation, who subsequently had positive GBS test results after 39 weeks' gestation.
From 2006 to 2007, we recruited 150 pregnant women who received routine GBS culture screening at 35 weeks' gestation with negative results, and who had repeat cultures and real-time polymerase chain reaction (RT-PCR) tests for GBS after 39 weeks' gestation.
Two percent of pregnant women with GBS-negative results by culture screening at 35 weeks' gestation were GBS-positive at 39 weeks' gestation.
It is necessary to perform a GBS test 4 weeks after an initial negative GBS culture at 35-37 weeks of gestation. RT-PCR provides a simple and rapid alternative method for detecting rectovaginal GBS colonization at the time of labor.
本研究旨在评估妊娠35周时B族链球菌（GBS）培养筛查结果为阴性的孕妇中，在妊娠39周后GBS检测结果转为阳性的比例。
2006年至2007年，我们招募了150名孕妇，她们在妊娠35周时接受了常规GBS培养筛查，结果为阴性，并且在妊娠39周后再次进行了GBS培养及实时聚合酶链反应（RT-PCR）检测。
妊娠35周时GBS培养筛查结果为阴性的孕妇中，有2%在妊娠39周时GBS检测结果为阳性。
在妊娠35 - 37周初次GBS培养结果为阴性后4周进行GBS检测是必要的。RT-PCR为分娩时检测直肠阴道GBS定植提供了一种简单快速的替代方法。
