School of Chemistry, University of Southampton, Southampton, UKSO17 1BJ.
Org Biomol Chem. 2010 Jan 7;8(1):24-8. doi: 10.1039/b913300n. Epub 2009 Nov 10.
There is currently much excitement surrounding the rapidly growing discipline of synthetic biology, which utilizes the design and construction principles of engineering to develop, evolve and standardize biological components and systems. This systematic approach to improving and increasing the programmability and robustness of biological components is expected to lead to the facile assembly of artificial biological components and integrated systems that enable innovative approaches to solving a wide range of societal challenges. Here we discuss the current state of the art and outline the next wave of synthetic biology: integrating individual components into systems.
目前,合成生物学这一快速发展的学科领域引起了广泛关注,该学科利用工程设计和构建原理来开发、进化和标准化生物组件和系统。这种系统的方法可以改善和增强生物组件的可编程性和鲁棒性,有望实现人工生物组件和集成系统的轻松组装,从而为解决广泛的社会挑战提供创新方法。在这里,我们讨论了当前的艺术状态,并概述了下一波合成生物学:将单个组件集成到系统中。