化学连接策略在糖肽和糖蛋白合成中的研究进展。
Advances in chemical ligation strategies for the synthesis of glycopeptides and glycoproteins.
机构信息
School of Chemistry, The University of Sydney, Sydney, Australia.
出版信息
Chem Commun (Camb). 2010 Jan 7;46(1):21-43. doi: 10.1039/b913845e. Epub 2009 Oct 30.
DOI:10.1039/b913845e
PMID:20024291
Abstract
A number of recent advances in the chemical synthesis of glycopeptides and glycoproteins are described, with particular focus on the development of peptide ligation strategies and their implementation in the convergent assembly of complex glycopeptides. Recent applications in the synthesis of full length homogeneous glycoproteins are also highlighted.
摘要
本文描述了糖肽和糖蛋白化学合成方面的一些最新进展，特别关注了肽连接策略的发展及其在复杂糖肽的收敛性组装中的应用。文中还强调了其在全长均一糖蛋白合成方面的最新应用。
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