用表面成像3D成像技术观察脊椎动物胚胎。
Visualizing vertebrate embryos with episcopic 3D imaging techniques.
作者信息
Geyer Stefan H, Mohun Timothy J, Weninger Wolfgang J
机构信息
Centre for Anatomy and Cell Biology, Medical University of Vienna, London.
出版信息
ScientificWorldJournal. 2009 Dec 16;9:1423-37. doi: 10.1100/tsw.2009.154.
The creation of highly detailed, three-dimensional (3D) computer models is essential in order to understand the evolution and development of vertebrate embryos, and the pathogenesis of hereditary diseases. A still-increasing number of methods allow for generating digital volume data sets as the basis of virtual 3D computer models. This work aims to provide a brief overview about modern volume data-generation techniques, focusing on episcopic 3D imaging methods. The technical principles, advantages, and problems of episcopic 3D imaging are described. The strengths and weaknesses in its ability to visualize embryo anatomy and labeled gene product patterns, specifically, are discussed.
为了理解脊椎动物胚胎的进化与发育以及遗传性疾病的发病机制，创建高度详细的三维（3D）计算机模型至关重要。越来越多的方法可用于生成数字体数据集，作为虚拟3D计算机模型的基础。这项工作旨在简要概述现代体数据生成技术，重点是表面3D成像方法。描述了表面3D成像的技术原理、优点和问题。具体讨论了其在可视化胚胎解剖结构和标记基因产物模式方面的优缺点。
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