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儿科心导管术不良事件的预防和早期干预的重要性:三年经验回顾。

Importance of prevention and early intervention of adverse events in pediatric cardiac catheterization: a review of three years of experience.

机构信息

Division of Pediatric Cardiology, Department of Pediatrics, China Medical University Hospital, Taichung, Taiwan.

出版信息

Pediatr Neonatol. 2009 Dec;50(6):280-6. doi: 10.1016/S1875-9572(09)60078-4.

Abstract

BACKGROUND

In spite of advances in many noninvasive instruments for studying cardiac anomalies in children, cardiac catheterization (CC) is still an essential method for the precise calculation of cardiovascular hemodynamic status and for performing therapeutic interventions. Accordingly, all adverse events (AE) related to CC are a major concern to pediatric cardiologists.

PATIENTS AND METHODS

A total of 220 children with congenital heart disease (CHD) who received cardiac catheterization in our tertiary care hospital between the period of January 2000 and December 2002 were studied. One hundred and thirty-eight patients were non-cyanotic CHD, 71 were cyanotic CHD and 11 were complex CHD. Diagnostic CC was performed in 138 patients and therapeutic CC in 82 patients. All AEs that occurred during the CC procedures were identified, recorded and managed at the scene. The severities of AE were further classified into minor, obvious and severe.

RESULTS

AEs were observed in 41 patients, including 22 (10%) minor, 16 (7.27%) obvious and 3 (1.36%) severe AEs. The three severe AEs were cardiac tamponade, severe ventricular tachycardia and marked hypoxia-and-bradycardia. None of the patients died. Therapeutic CC did not present a higher incidence of AE occurrence than diagnostic CC. However, a young age (p<0.0001), low body weight (p<0.0001) and cyanotic or complex CHD (p=0.01) appeared to be risk factors for obvious and severe AE.

CONCLUSION

Although the complication of severe AE during CC may not be totally preventable, it is important to be aware of every early sign of AE and to initiate an effective intervention by a well trained resuscitation team.

摘要

背景

尽管在研究儿童心脏异常的许多无创仪器方面取得了进步,但心导管检查(CC)仍然是精确计算心血管血液动力学状态和进行治疗干预的重要方法。因此,所有与 CC 相关的不良事件(AE)都是儿科心脏病专家关注的主要问题。

患者和方法

本研究共纳入 2000 年 1 月至 2002 年 12 月在我院接受心导管检查的 220 例先天性心脏病(CHD)患儿。138 例为非发绀性 CHD,71 例为发绀性 CHD,11 例为复杂 CHD。138 例患儿行诊断性 CC,82 例患儿行治疗性 CC。所有在 CC 过程中发生的 AE 均被识别、记录并在现场进行处理。AE 的严重程度进一步分为轻度、中度和重度。

结果

41 例患儿出现 AE,其中 22 例(10%)为轻度,16 例(7.27%)为中度,3 例(1.36%)为重度。三种严重 AE 为心脏压塞、严重室性心动过速和明显缺氧-心动过缓。无患儿死亡。治疗性 CC 并不比诊断性 CC 更易发生 AE。然而,年龄较小(p<0.0001)、体重较低(p<0.0001)以及发绀或复杂 CHD(p=0.01)似乎是中重度 AE 的危险因素。

结论

尽管 CC 期间严重 AE 的并发症可能无法完全预防,但重要的是要注意到每一个 AE 的早期迹象,并通过训练有素的复苏团队进行有效的干预。

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