From the Department of Cardiac Anesthesia, Boston Children's Hospital, Boston, Massachusetts.
Anesth Analg. 2014 Jan;118(1):175-82. doi: 10.1213/ANE.0b013e3182908bcb.
Cardiac catheterization for patients with congenital heart disease has shifted from diagnostic to predominantly interventional procedures because of advances in catheter-based technologies. Children undergoing therapeutic catheterization may be at higher risk of adverse events, and the purpose of our study was to determine the incidence of cardiac arrest (CA) in patients with congenital heart disease undergoing cardiac catheterization at a large pediatric tertiary referral center.
All CAs from January 2004 through December 2009 occurring in the cardiac catheterization laboratory were reviewed. A CA was defined as an event in which cessation of circulation required chest compressions. Procedure, patient, practitioner, and system-related factors were examined.
Over the study period, during 7289 catheterization procedures, 70 procedures were associated with a CA (0.96 [99% confidence interval, 0.7-1.3] per 100 procedures); 48 events (69%) were successfully resuscitated to a perfusing rhythm, 18 events (26%) resulted in need for extracorporeal membrane oxygenation, and 4 events (6%) resulted in unsuccessful resuscitation. Sudden onset of cardiac arrhythmia led to CA during 38 events (54%). The duration of resuscitation after CA was ≤11 minutes in 71%. Occurrence of CA was associated with interventional procedures (P < 0.001) and younger age (P < 0.001). A change in systems for scheduling and communication of cases was associated with a significant reduction in the incidence of CA (1.5% vs 0.7%; P = 0.002).
The incidence of CA in children undergoing cardiac catheterization is high compared with pediatric noncardiac surgery. Procedural and system factors were associated with occurrence of CA in this cohort. These issues highlight the need for close communication, anticipation, and preparation.
由于导管技术的进步,先天性心脏病患者的心脏导管检查已从诊断性转变为主要的介入性操作。接受治疗性导管检查的儿童发生不良事件的风险可能更高,本研究的目的是确定在大型儿科三级转诊中心接受心脏导管检查的先天性心脏病患者中心脏骤停(CA)的发生率。
回顾了 2004 年 1 月至 2009 年 12 月期间在心脏导管实验室发生的所有 CA。CA 定义为循环停止需要胸部按压的事件。检查了程序、患者、医生和系统相关因素。
在研究期间,在 7289 例导管检查过程中,有 70 例与 CA 相关(每 100 例中 0.96 [99%置信区间,0.7-1.3]);48 例事件(69%)成功复苏至灌注节律,18 例事件(26%)需要体外膜氧合,4 例事件(6%)复苏不成功。38 例(54%)CA 突然发生心律失常。CA 后复苏时间≤11 分钟的发生率为 71%。CA 的发生与介入性操作(P<0.001)和年龄较小(P<0.001)有关。病例安排和沟通系统的改变与 CA 发生率的显著降低有关(1.5%比 0.7%;P=0.002)。
与儿科非心脏手术相比,儿童接受心脏导管检查时 CA 的发生率较高。本队列中,程序和系统因素与 CA 的发生有关。这些问题强调了密切沟通、预测和准备的必要性。