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早孕合并脑静脉窦血栓形成:原发性抗磷脂综合征的一种罕见表现。

Cerebral venous sinus thrombosis in early pregnancy: an unusual presentation of primary antiphospholipid syndrome.

作者信息

Hanprasertpong Tharangrut, Hanprasertpong Jitti, Riabroi Kittipong

机构信息

Department of Obstetrics and Gynecology, Faculty of Medicine, Prince of Songkla University, Songkhla, Thailand.

出版信息

J Obstet Gynaecol Res. 2009 Dec;35(6):1125-8. doi: 10.1111/j.1447-0756.2009.01088.x.

Abstract

Cerebral venous sinus thrombosis, an unusual presentation of antiphospholipid syndrome, is a rare condition in pregnancy, particularly in the first trimester. The authors of this case report present the case of a 20-year-old woman with sudden onset of headaches and hemiparesis in the first trimester of pregnancy. She underwent a computed tomography scan and magnetic resonance imaging. The image findings and the autoimmune serum test were consistent with a cerebral venous sinus thrombosis complicated by primary antiphospholipid syndrome. The patient's hemiparesis improved with subcutaneous low molecular weight heparin and oral aspirin. In the third trimester of pregnancy, she developed seizures that were controlled by antiepileptic drugs. She delivered a healthy baby at 37 weeks' gestation without immediate or late postpartum complications.

摘要

脑静脉窦血栓形成是抗磷脂综合征的一种不寻常表现,在妊娠期较为罕见,尤其是在孕早期。本病例报告的作者介绍了一名20岁女性的病例,该女性在妊娠早期突然出现头痛和偏瘫。她接受了计算机断层扫描和磁共振成像检查。影像学检查结果和自身免疫血清检测结果与原发性抗磷脂综合征并发脑静脉窦血栓形成相符。皮下注射低分子量肝素和口服阿司匹林后,患者的偏瘫症状有所改善。在妊娠晚期,她出现了癫痫发作,通过抗癫痫药物得到了控制。她在妊娠37周时分娩了一个健康的婴儿,没有出现产后即刻或晚期并发症。

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