Department of Laboratory Medicine, Collegium Medicum, Nicolaus Copernicus University, ul. M.Sklodowskiej-Curie 9, 85-094 Bydgoszcz, Poland.
Clin Biochem. 2010 Apr;43(6):626-8. doi: 10.1016/j.clinbiochem.2009.12.013. Epub 2009 Dec 21.
Third generation oral contraceptives (OC) may increase the risk of cardiovascular events in healthy young women.
We assessed the effect of second and third generation OC on CRP, lipids and apolipoproteins in 128 women.
CRP was significantly higher in third generation contraceptive users. The main determinant of CRP in OC users was triglycerides.
Young women using oral contraceptives, especially third generation formulas, might not be free of cardiovascular risk having increased CRP concentration.
第三代口服避孕药（OC）可能会增加健康年轻女性发生心血管事件的风险。
我们评估了第二代和第三代 OC 对 128 名女性 CRP、血脂和载脂蛋白的影响。
第三代避孕药使用者的 CRP 显著升高。OC 使用者 CRP 的主要决定因素是甘油三酯。
使用口服避孕药的年轻女性，尤其是第三代配方，可能会因 CRP 浓度升高而面临心血管风险。
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