J Craig Venter Institute, 9704 Medical Center Drive, Rockville, MD 20850, USA.
Br J Cancer. 2010 Jan 19;102(2):243-8. doi: 10.1038/sj.bjc.6605497. Epub 2009 Dec 22.
Recent advances in DNA sequencing technology are providing unprecedented opportunities for comprehensive analysis of cancer genomes, exomes, transcriptomes, as well as epigenomic components. The integration of these data sets with well-annotated phenotypic and clinical data will expedite improved interventions based on the individual genomics of the patient and the specific disease.
近年来,DNA 测序技术的进步为全面分析癌症基因组、外显子组、转录组以及表观基因组成分提供了前所未有的机会。将这些数据集与标注良好的表型和临床数据相结合,将加速基于患者个体基因组和特定疾病的改进干预措施的实施。