Rader J S, Leake J F, Dillon M B, Rosenshein N B
Department of Gynecology and Obstetrics, Johns Hopkins Hospital, Baltimore, Maryland.
Obstet Gynecol. 1991 Apr;77(4):573-6.
Ultrasonic surgical aspiration is a useful technique for safe and accurate tissue removal. This study was conducted to evaluate its role in noninvasive vulvar disease. From December 1988 to March 1990, 27 patients underwent ultrasonic surgery; nine patients had vulvar intraepithelial neoplasia (VIN) and 18 had condylomata acuminata. All surgical procedures were done under general anesthesia, with two patients requiring hospitalization for perineal care and pain control after extensive vulvar surgery. Recurrent or persistent disease occurred in four patients with condylomata acuminata and in two with VIN, with a mean follow-up of 50 weeks. Reepithelialization was completed within 5 weeks and no patients developed vulvar scarring. Adequate samples for histopathologic review were obtained in 26 patients. Identical histologic grading occurred in all 13 patients who had preoperative vulvar biopsies and an adequate aspiration specimen. Ultrasonic surgery permits precise and rapid removal of epithelial lesions with rapid healing, minimal patient discomfort, excellent cosmetic results, and histopathologic documentation.
超声手术吸引术是一种安全、准确地切除组织的有用技术。本研究旨在评估其在无创性外阴疾病中的作用。1988年12月至1990年3月，27例患者接受了超声手术；9例患者患有外阴上皮内瘤变（VIN），18例患有尖锐湿疣。所有手术均在全身麻醉下进行，2例患者在广泛外阴手术后因会阴护理和疼痛控制需要住院治疗。尖锐湿疣患者中有4例、VIN患者中有2例出现复发或持续性疾病，平均随访50周。上皮再形成在5周内完成，无患者出现外阴瘢痕形成。26例患者获得了足够的组织样本用于组织病理学检查。在所有13例术前进行外阴活检并获得足够的吸引样本的患者中，组织学分级相同。超声手术能够精确、快速地切除上皮病变，愈合迅速，患者不适最小，美容效果极佳，且有组织病理学记录。
