Remmenga S, Barnhill D, Nash J, Bosscher J, Teneriello M, Park R
Department of Obstetrics and Gynecology, Uniformed Services University of the Health Sciences, Bethesda, Maryland.
Obstet Gynecol. 1991 Apr;77(4):577-9.
The patient with carcinoma of the vulva may present with tumor involvement of the perirectal area. Traditional treatment has often involved ultraradical therapy including a radical vulvectomy with posterior or total pelvic exenteration in an effort to obtain adequate surgical margins. Five-year survival rates for these patients range from 20-50%, and major operative morbidity as well as psychological problems are associated with this extensive surgery. Five patients treated for a locally advanced vulvar carcinoma involving the perirectal area were thought to be candidates for a rectum-sparing procedure. They underwent a radical vulvectomy, bilateral inguinal lymphadenectomy, partial rectal resection, and a diverting colostomy. Four of the five patients agreed to a colostomy closure 6 months after their primary therapy; these four patients have resumed normal bowel function. All patients remain clinically free of tumor.
外阴癌患者可能出现肿瘤累及直肠周围区域的情况。传统治疗通常采用超根治性疗法,包括根治性外阴切除术及后路或全盆腔脏器清除术,以获得足够的手术切缘。这些患者的五年生存率为20%至50%,且这种广泛手术会伴有严重的手术并发症以及心理问题。五名接受治疗的局部晚期外阴癌累及直肠周围区域的患者被认为适合保留直肠的手术。他们接受了根治性外阴切除术、双侧腹股沟淋巴结清扫术、部分直肠切除术及转流性结肠造口术。五名患者中有四名在初次治疗6个月后同意关闭结肠造口;这四名患者已恢复正常肠道功能。所有患者临床均无肿瘤。