Tworzydlo Waclaw, Kloc Malgorzata, Bilinski Szczepan M
Department of Systematic Zoology, Institute of Zoology, Jagiellonian University, Krakow, Poland.
J Morphol. 2010 May;271(5):634-40. doi: 10.1002/jmor.10824.
Stem cells function in niches, which consist of somatic cells that control the stem cells' self-renewal, proliferation, and differentiation. Drosophila ovary germline niche consists of the terminal filament (TF) cells, cap cells, and escort stem cells; signaling from the TF cells and the cap cells is essential for maintenance of germline stem cells (GSCs). Here, we show that in the earwig Opisthocosmia silvestris, the female GSC niche is morphologically simple and consist of the TF cells and several structurally uniform escort cells. The most posterior cell of the TF (the basal cell of the TF) differs from remaining TF cells and is separated from the anterior region of the germarium by the processes of the escort cells, and consequently, does not contact the GSCs directly. We also show that between somatic cells of earwig niche argosome-like vesicles and cytoneme-like extensions are present.
干细胞在小生境中发挥作用，小生境由控制干细胞自我更新、增殖和分化的体细胞组成。果蝇卵巢生殖系小生境由终端丝（TF）细胞、帽细胞和护送干细胞组成；来自TF细胞和帽细胞的信号对于生殖系干细胞（GSC）的维持至关重要。在这里，我们表明，在蠼螋Opisthocosmia silvestris中，雌性GSC小生境在形态上很简单，由TF细胞和几个结构均匀的护送细胞组成。TF最靠后的细胞（TF的基底细胞）与其余TF细胞不同，并且被护送细胞的突起与卵巢管的前部区域隔开，因此不直接接触GSC。我们还表明，在蠼螋小生境的体细胞之间存在类无颗粒小泡和类丝状伪足样延伸。
