Hospital Central Dr. Ignacio Morones Prieto, San Luis Potosi, Mexico.
Emerg Infect Dis. 2010 Jan;16(1):27-34. doi: 10.3201/eid1601.090941.
We describe the clinical characteristics and outcomes of adults hospitalized with pneumonia during the pandemic (H1N1) 2009 outbreak. Patients admitted to a general hospital in San Luis Potosí, Mexico, from April 10 through May 11, 2009, suspected to have influenza virus-associated pneumonia were evaluated. We identified 50 patients with suspected influenza pneumonia; the presence of influenza virus was confirmed in 18: 11 with pandemic (H1N1) 2009 virus, 5 with unsubtypeable influenza A virus, 1 with seasonal influenza A virus (H3N2), and 1 in whom assay results for seasonal and pandemic (H1N1) 2009 viruses were positive. Eighteen patients were treated in the intensive care unit, and 10 died. During the pandemic (H1N1) 2009 outbreak, severe pneumonia developed in young adults who had no identifiable risk factors; early diagnosis and treatment of influenza virus infections may have a determinant role in outcome.
我们描述了大流行(H1N1)2009 爆发期间因肺炎住院的成年人的临床特征和结局。2009 年 4 月 10 日至 5 月 11 日,对墨西哥圣路易斯波托西州一家综合医院收治的疑似流感病毒相关肺炎的患者进行了评估。我们确定了 50 名疑似流感肺炎患者;在 18 例中证实存在流感病毒:11 例为大流行(H1N1)2009 病毒,5 例为不可分型流感 A 病毒,1 例为季节性流感 A 病毒(H3N2),1 例季节性和大流行(H1N1)2009 病毒检测结果均为阳性。18 名患者在重症监护病房接受治疗,10 名患者死亡。在大流行(H1N1)2009 爆发期间,年轻成年人出现了无明确危险因素的严重肺炎;早期诊断和治疗流感病毒感染可能对结局具有决定性作用。