Department of Surgery, Mayo Clinic, Rochester, MN 55905, USA.
J Pediatr Gastroenterol Nutr. 2009 Oct;49(4):430-4. doi: 10.1097/01.mpg.0000361657.54810.19.
Pancreatitis is a known complication of endoscopic retrograde cholangiopancreatography (ERCP). Our aim was to assess the prevalence and severity of ERCP-associated pancreatitis using established criteria.
Retrospective review of patients younger than 18 years undergoing ERCP complicated by post-ERCP pancreatitis defined by the 1991 consensus statement. Patients with chronic pancreatitis were studied separately using modified criteria. Risk factors for post-ERCP pancreatitis were analyzed.
Three hundred forty-three ERCPs were performed in 224 patients. Two hundred seventy-six ERCPs were performed in patients without chronic pancreatitis, 7 of which were complicated by post-ERCP pancreatitis (prevalence 2.5%). Patients undergoing diagnostic-only ERCP were less likely to develop post-ERCP pancreatitis (P<0.01). Sixty-seven procedures were performed on patients with chronic pancreatitis; 10 developed postprocedure pain requiring or prolonging hospitalization (prevalence 14.9%). Pancreatic duct stenting was a risk factor for post-ERCP pain in this subset of patients (P=0.02).
The prevalence of post-ERCP pancreatitis is low-2.5% excluding patients with chronic pancreatitis and 4.96% overall. Therapeutic procedures and the presence of chronic pancreatitis are risk factors for post-ERCP pancreatitis.
胰腺炎是内镜逆行胰胆管造影术(ERCP)的已知并发症。我们的目的是使用既定标准评估与 ERCP 相关的胰腺炎的发生率和严重程度。
回顾性分析年龄小于 18 岁且符合 1991 年共识标准的 ERCP 术后并发胰腺炎的患者。使用改良标准单独研究慢性胰腺炎患者。分析与 ERCP 后胰腺炎相关的危险因素。
224 名患者共进行了 343 次 ERCP。276 次 ERCP 用于无慢性胰腺炎的患者,其中 7 次并发 ERCP 后胰腺炎(发生率 2.5%)。仅行诊断性 ERCP 的患者发生 ERCP 后胰腺炎的可能性较低(P<0.01)。67 例患者行慢性胰腺炎 ERCP,其中 10 例术后出现疼痛,需住院或延长住院时间(发生率 14.9%)。在这组患者中,胰管支架置入是 ERCP 术后疼痛的危险因素(P=0.02)。
排除慢性胰腺炎患者后,ERCP 后胰腺炎的发生率较低,为 2.5%,总体发生率为 4.96%。治疗性操作和慢性胰腺炎的存在是 ERCP 后胰腺炎的危险因素。