First Department of Orthopedics, Athens University Medical School, Athens, Greece.
Eur J Phys Rehabil Med. 2009 Dec;45(4):501-6. Epub 2009 Jan 21.
Botulinum toxin A injections and orthotics have been used to manage upper extremity spasticity in hemiplegic children. The authors performed a study to evaluate the necessity and effectiveness of a static night splint following outpatient botulinum toxin A treatment in children with upper limb spastic cerebral palsy.
Twenty children with upper limb spastic cerebral palsy were treated with botulinum toxin A injections. A static night splint was applied in half of them. Objective assessment of upper limb function was performed at baseline, at 2 and 6 months after botulinum toxin A injection using the Quality of Upper Extremity Skills Test.
After botulinum toxin A treatment, both groups showed an improvement on their previous functional level of the injected upper extremity. At 2 months, children in group A showed a 15.4% improvement, whereas children in group B improved by 12.2% from baseline; these were not statistically significant (P=0.326). At 6 months, group A still maintained a 15.9% improvement in function compared to group B which differed only by 4.2% from prebotulinum toxin A baseline; these differences were statistically significant (P=0.000). Complications related to the botulinum toxin A injection were not observed. The static
Static night splinting following botulinum toxin A injections has shown a definite treatment effect in reducing spasticity and improving function in children with upper limb spastic cerebral palsy.
肉毒毒素 A 注射和矫形器已被用于治疗偏瘫儿童的上肢痉挛。作者进行了一项研究，以评估在门诊肉毒毒素 A 治疗后，上肢痉挛性脑瘫儿童使用静态夜间夹板的必要性和有效性。
20 名上肢痉挛性脑瘫儿童接受肉毒毒素 A 注射治疗。其中一半接受静态夜间夹板治疗。使用上肢技能测试质量评估工具，在基线、肉毒毒素 A 注射后 2 个月和 6 个月对上肢功能进行客观评估。
肉毒毒素 A 治疗后，两组上肢的注射侧功能均有改善。2 个月时，A 组儿童的改善率为 15.4%，而 B 组儿童的改善率为 12.2%，两组间无统计学差异（P=0.326）。6 个月时，A 组与 B 组相比，功能仍保持 15.9%的改善，而 B 组与肉毒毒素 A 治疗前基线相比仅改善 4.2%，差异有统计学意义（P=0.000）。未观察到与肉毒毒素 A 注射相关的并发症。
肉毒毒素 A 注射后使用静态夜间夹板治疗可显著降低上肢痉挛性脑瘫儿童的痉挛程度，改善其功能。
