[Studies on the chemical constituents from Euphorbia chrysocoma].

OBJECTIVE

To study the chemical constituents from the aerial part of Euphorbia chrysocoma.

METHODS

All compounds were isolated and purified by many methods, including siliga gel and reversed phase RP-18 column chromatographies, preparative thin layer chromatography, Sephadex LH-20, and recrystallization. Their structures were mainly elucidated by ESI-MS and NMR spectra and their physical characters.

RESULTS

Six compounds were isolated from the petroleum ether section from 75% ethanol extraction of the material. Their structures were identified as taraxerol (1), epitaraxerol (2), beta-sistosterol (3), beta-sitostenone (4), jolkinolide E (5), and sesamin (6).

CONCLUSION

Compounds 1, 2, 4, 5, and 6 are isolated from this plant for the first time.