戈谢病-斯托特病患者病理性骨折的保守治疗。
Conservative treatment of a pathologic fracture in a patient with Gorham-Stout disease.
作者信息
Pedroletti Fred, Rangarajan Shrinivas, McCain Joseph P, Velez Ines
机构信息
Resident, Oral and Maxillofacial Surgery, College of Dental Medicine, Nova Southeastern University, Fort Lauderdale, FL.
出版信息
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010 Feb;109(2):e49-52. doi: 10.1016/j.tripleo.2009.08.045.
Gorham-Stout disease, or massive osteolysis, is an extremely rare idiopathic condition characterized by spontaneous, localized relentless resorption of one or several contiguous bones. There is no known successful treatment. Autologous bone graft also resorbs. It is a condition with difficult diagnosis, treatment, and prognosis. We report an extreme case of massive osteolysis of the maxillofacial complex. Unique to this case is that the patient presented with a mandibular fracture, and was taking alendronate (Fosamax), one of the treatment options for patients with Gorham-Stout disease. We discuss our treatment and add to the growing list of patients who have presented with this devastating disease.
戈勒姆-斯托特病，即大块骨质溶解症，是一种极其罕见的特发性疾病，其特征为一个或多个相邻骨骼出现自发性、局限性、持续性骨质吸收。目前尚无已知的成功治疗方法。自体骨移植也会被吸收。这是一种诊断、治疗和预后都很困难的疾病。我们报告一例颌面复合体大块骨质溶解的极端病例。该病例的独特之处在于患者出现下颌骨骨折，且正在服用阿仑膦酸盐（福善美），这是戈勒姆-斯托特病患者的治疗选择之一。我们讨论了我们的治疗方法，并补充到患有这种毁灭性疾病的患者名单中。
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