Department of Chemistry, Purdue University, West Lafayette, IN 47907, USA.
Curr Opin Chem Biol. 2010 Apr;14(2):276-83. doi: 10.1016/j.cbpa.2009.11.009. Epub 2009 Dec 28.
The oceans are filled with an amazing variety of biological materials including the glues and cements of mussels, barnacles, tube worms, algae, and starfish. Recent studies on mussel adhesive are providing increasing evidence for a unique mechanism of material generation involving iron-induced protein oxidation and cross-linking chemistry. Insights are also being gathered on many of the other marine creatures producing adhesives. Beyond understanding biology, this growing knowledge is inspiring application development. New classes of biomimetic polymers are poised to provide the next generation of surgical adhesives and orthopedic cements.
海洋中充满了各种神奇的生物材料,包括贻贝、藤壶、管虫、藻类和海星的胶和水泥。最近对贻贝粘合剂的研究为一种独特的材料生成机制提供了越来越多的证据,涉及铁诱导的蛋白质氧化和交联化学。人们对许多其他产生粘合剂的海洋生物也有了更多的了解。除了了解生物学之外,这方面的知识还激发了应用的发展。新型仿生聚合物有望为下一代手术粘合剂和骨科水泥提供支持。