Santana Orlando, Panchamukhi Kshamaya B, Grana Roberto, Traad Ernest A
Echocardiography Laboratory, Mount Sinai Medical Center, 4300 Alton Rd, Miami Beach, Florida 33140, USA.
Heart Surg Forum. 2009 Dec;12(6):E320-3. doi: 10.1532/HSF98.20091056.
We retrospectively evaluated the results of edge-to-edge (Alfieri) repair of the mitral valve via a transaortic approach in patients undergoing aortic valve replacement (AVR) and who had significant mitral regurgitation (MR).
From July 2000 to June 2006, 13 patients underwent edge-to-edge repair of the mitral valve via a transaortic approach with concomitant AVR. Patients were considered eligible for the transaortic Alfieri repair if the preoperative transesophageal echocardiogram indicated that the MR jet originated in the middle portion (A2/P2 segments) of the mitral valve. A postoperative transesophageal echocardiogram and follow-up transthoracic echocardiograms were obtained.
There was no operative mortality. There was a significant improvement in the median MR grade from 3 (interquartile range [IQR], 2-4) preoperatively to 1 (IQR, 1-1) postoperatively (P < .0001). The ejection fraction (EF) remained stable, with mean preoperative and postoperative EFs of 44.2% + or - 14.9% and 46.27% + or - 11.6%, respectively (P = .4). No mitral stenosis was noted in any of the patients following edge-to-edge repair. Follow-up transthoracic echocardiograms obtained at a mean of 12.5 months postoperatively (range, 1-34 months) showed a median MR grade of 1 (IQR, 1-2) with no worsening compared with immediately postoperatively (P = .4).
Transaortic edge-to-edge repair of the mitral valve in patients undergoing AVR is feasible. The postoperative improvement in MR was maintained at the midterm follow-up.
我们回顾性评估了在接受主动脉瓣置换术(AVR)且有显著二尖瓣反流(MR)的患者中,经主动脉途径进行二尖瓣缘对缘(Alfieri)修复的结果。
2000年7月至2006年6月,13例患者经主动脉途径进行二尖瓣缘对缘修复并同期行AVR。如果术前经食管超声心动图显示MR喷射起源于二尖瓣的中部(A2/P2节段),则认为患者适合行经主动脉Alfieri修复。术后获得经食管超声心动图和随访经胸超声心动图。
无手术死亡。MR分级中位数从术前的3级(四分位间距[IQR],2 - 4)显著改善至术后的1级(IQR,1 - 1)(P <.0001)。射血分数(EF)保持稳定,术前和术后平均EF分别为44.2%±14.9%和46.27%±11.6%(P =.4)。缘对缘修复后所有患者均未发现二尖瓣狭窄。术后平均12.5个月(范围1 - 34个月)获得的随访经胸超声心动图显示MR分级中位数为1级(IQR,1 - 2),与术后即刻相比无恶化(P =.4)。
在接受AVR的患者中,经主动脉二尖瓣缘对缘修复是可行的。中期随访时MR的术后改善得以维持。