Yasumoto Taku, Shimizu Junzo, Watanabe Noriyuki, Inada Masami, Nakata Saki, Sato Masayuki, Hayashi Shoho, Dono Keizo, Kitada Masashi, Shimano Takashi
Department of Radiology, Toyonaka Municipal Hospital.
Gan To Kagaku Ryoho. 2009 Nov;36(12):2093-5.
The case is a man in his 50s who had a curative surgical resection for cholangiocarcinoma in August 2006. The lesion was judged to be T3, N1, H0, P0, M0 and Stage III, and then he received various treatments including thermotherapy, CD3-activated T lymphocyte therapy. Then from June 2007, he was treated for multiple liver metastases by GEM, radiofrequency ablation (RFA), stereotactic radiotherapy, S-1, dendritic cell therapy. But there were multiple liver metastases whose maximum size was 17 mm in diameter and he was introduced to our hospital. In September 2008, ultrasonography and CT fluoroscopy guided RFA was operated on him for the liver tumors with a safety margin. But 2 hours after the ablation, he complained of epigastralgia. CT examination revealed a bile peritonitis caused by perforation of the jejunum which has been anastomosed to the pancreas, and was adjacent to the avascular area caused by RFA in segment 4 of the liver. We treated him by various interventional procedures including percutaneous drainage for bile leakage, pancreatic fistula, abscess in peritoneal cavity, and biloma in segment 3. Fifty days after the ablation, T-tube, with which pancreatic fluid and bile was induced from the cecal portion of the anastomosed jejunum to the anal side slipping through the perforated point, was successfully inserted through right flank, and resulted in complete recovery from a major technical complication of the bile peritonitis.
该病例为一名50多岁男性,于2006年8月接受了胆管癌根治性手术切除。病变被判定为T3、N1、H0、P0、M0,处于III期,随后他接受了包括热疗、CD3激活的T淋巴细胞疗法在内的多种治疗。然后从2007年6月起,他接受了吉西他滨、射频消融(RFA)、立体定向放疗、S-1、树突状细胞疗法治疗多发性肝转移。但仍存在多发性肝转移,最大直径为17毫米,随后他被转诊至我院。2008年9月,在超声和CT透视引导下对他的肝脏肿瘤进行了带安全边缘的RFA治疗。但消融术后2小时,他主诉上腹部疼痛。CT检查显示空肠穿孔导致胆汁性腹膜炎,该空肠已与胰腺吻合,且靠近肝脏第4段RFA造成的无血管区。我们通过各种介入程序对他进行治疗,包括对胆汁漏、胰瘘、腹腔脓肿和第3段胆汁瘤进行经皮引流。消融术后50天,成功地从右侧腹插入T形管,通过穿孔点将吻合空肠盲肠部的胰液和胆汁引流至肛门侧,胆汁性腹膜炎这一主要技术并发症得以完全康复。