Slakey Douglas P
Department of Surgery, Tulane Center for Abdominal Transplantation, Tulane University Hospital and Clinic, New Orleans, Louisiana 70112, USA.
Am Surg. 2002 Apr;68(4):395-7.
Intrahepatic recurrence of cholangiocarcinoma after primary resection has traditionally been considered a contraindication to surgical management. Improvements in ablative technologies such as radiofrequency ablation (RFA) offer the surgeon additional alternatives in the management of selected intrahepatic tumors. We present a case report of a single intrahepatic recurrence of cholangiocarcinoma 12 months after primary resection of extrahepatic cholangiocarcinoma including right lobectomy for intrahepatic extension. The patient received operative treatment and RFA of the intrahepatic lesion. RFA successfully ablated the recurrent tumor, and the patient remains free of detectable disease 10 months later. A review of literature is presented. This is the first known report of the use of RFA for intrahepatic cholangiocarcinoma. In selected cases of primary or recurrent cholangiocarcinoma, RFA may increase the percentage of patients considered surgically treatable.
肝外胆管癌初次切除术后肝内复发传统上被视为手术治疗的禁忌证。诸如射频消融(RFA)等消融技术的进步为外科医生在治疗特定肝内肿瘤方面提供了更多选择。我们报告一例肝外胆管癌初次切除术后12个月发生单一肝内复发的病例,初次切除包括因肝内侵犯而行右半肝切除术。患者接受了手术治疗及肝内病灶的射频消融。射频消融成功地消融了复发性肿瘤,10个月后患者仍未发现疾病。本文还对文献进行了综述。这是已知的首例使用射频消融治疗肝内胆管癌的报告。在原发性或复发性胆管癌的特定病例中,射频消融可能会增加可接受手术治疗患者的比例。