Matsuyama Jin, Naitou Atsushi, Hiraki Masayuki, Matsumoto Shinji, Hashimoto Kazuhiko, Yokoyama Shigekazu, Morita Shunji, Morimoto Takashi, Fukushima Yukio, Nishishou Isamu, Nomura Takashi, Sasaki Yo
Department of Surgery, Yao Municipal Hospital.
Gan To Kagaku Ryoho. 2009 Nov;36(12):2297-9.
The patient was a 76-year-old man with advanced gastric cancer located in cardia, and was diagnosed to have an invasion to diaphragma and multiple lymph node metastases. We treated successfully with 12-course of S-1 chemotherapy. But second primary gastric cancer was detected in antrum 26 months after primary therapy. We treated with S-1/paclitaxel ( PTX) combined chemotherapy. S-1 (80 mg/m2) was orally administered for 2 weeks followed by a week interval and PTX (50 mg/m2) was also administered days 1 and 8. One course of chemotherapy was 21 days. GIF and abdominal CT revealed complete response (CR) after 3 courses of chemotherapy. We are now going on 6 courses of chemotherapy and the patient did not experience any grade 3 adverse effects.
该患者为一名76岁男性，患有位于贲门的晚期胃癌，诊断为侵犯膈肌并伴有多发淋巴结转移。我们成功地对其进行了12个疗程的S-1化疗。但在初次治疗26个月后，胃窦部发现了第二原发性胃癌。我们采用S-1/紫杉醇（PTX）联合化疗进行治疗。S-1（80mg/m²）口服2周，随后间隔1周，PTX（50mg/m²）在第1天和第8天给药。一个化疗疗程为21天。GIF和腹部CT显示在3个疗程化疗后达到完全缓解（CR）。我们目前正在进行6个疗程的化疗，患者未出现任何3级不良反应。
