Wilson W B, Manke W F
Department of Ophthalmology, University of Colorado Health Sciences Center, Denver.
Arch Ophthalmol. 1991 Mar;109(3):343-5. doi: 10.1001/archopht.1991.01080030045035.
We studied 42 orbits of 23 patients with Graves' disease who had proptosis secondary to the orbitopathy of their disease and had undergone decompressive operations. The patients were evaluated preoperatively and underwent computed tomography. They were also examined frequently during the first postoperative year and the computed tomography was repeated at 6 months. Three variables correlated well with the reduction in proptosis: the percentage of increase in orbital volume after surgery, the absolute increase in orbital volume, and the degree of orbital "stiffness" as measured preoperatively. The first two variables have an inverse correlation with the third. We refer to the loss of resilience of orbital tissues and the increase in adherence between tissue planes, collectively, as orbital "stiffness." While other factors, such as the size of the anterior opening of the orbit, the resistance of the lid diaphragm, and pressure changes within the orbit, may affect the resultant reduction in proptosis, we did not attempt to measure these factors.
我们研究了23例格雷夫斯病患者的42个眼眶，这些患者因疾病的眼眶病变继发眼球突出并接受了减压手术。患者在术前接受评估并进行计算机断层扫描。术后第一年还对他们进行了频繁检查，并在6个月时重复进行计算机断层扫描。有三个变量与眼球突出度的降低密切相关：术后眼眶容积增加的百分比、眼眶容积的绝对增加量以及术前测量的眼眶“硬度”。前两个变量与第三个变量呈负相关。我们将眼眶组织弹性的丧失以及组织平面之间粘连的增加统称为眼眶“硬度”。虽然其他因素，如眼眶前开口的大小、眼睑隔膜的阻力以及眼眶内的压力变化，可能会影响最终的眼球突出度降低，但我们并未试图测量这些因素。
