Kerman Oral and Dental Disease Research Center, Department of Oral Medicine, Kerman University of Medical Sciences, Shafa Street, Kerman, Iran.
Arch Iran Med. 2010 Jan;13(1):48-52.
Heck's disease or focal epithelial hyperplasia is a benign contagious disease caused by human papillomavirus types 13 or 32. It occurs with low frequency in the Iranian population. This condition is characterized by the occurrence of multiple, small papules or nodules in the oral cavity, especially on the labial and buccal mucosa and tongue. In some populations, up to 39% of children are affected. Conservative surgical excision of lesions may be performed for diagnostic or aesthetic purposes. The risk of recurrence after this therapy is minimal, and there seems to be no malignant transformation potential. In the present work, we presented the clinical case of a 12-year-old Iranian girl with oral lesions that clinically and histologically correspond to Heck's disease.
海克病或局灶性上皮增生是一种由人乳头瘤病毒 13 型或 32 型引起的良性传染病。在伊朗人群中发病率较低。这种疾病的特征是口腔内出现多个小丘疹或结节，尤其是唇和颊粘膜及舌部。在某些人群中，高达 39%的儿童受影响。为了诊断或美容目的，可对病变进行保守性外科切除。这种治疗后的复发风险极小，似乎没有恶变的潜力。在本工作中，我们报告了一例 12 岁伊朗女孩的临床病例，其口腔病变在临床上和组织学上与海克病相符。
