Borborema-Santos Cristina Maria, Castro Maria Marta de, Santos Paulo José Benevides dos, Talhari Sinésio, Astolfi-Filho Spartaco
Center of Multidisciplinary Support, Federal University of Amazonas, Manaus, AM, Brazil.
Braz Dent J. 2006;17(1):79-82. doi: 10.1590/s0103-64402006000100018. Epub 2006 May 2.
Focal epithelial hyperplasia or Heck's disease is a rare contagious disease caused by human papillomavirus types 13 or 32, initially described among Native American populations. This condition is characterized by the occurrence of multiple small papules or nodules in oral cavity, especially on labial and buccal mucosa and tongue. This report describes the diagnosis of focal epithelial hyperplasia in five Central Amazonian Indians who sought treatment at the Amazonas State Foundation of Tropical Medicine (FMT-AM), using clinical criteria, polymerase chain reaction (PCR) and DNA sequencing.
